Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis

Immune-regulatory mechanisms of drug-free remission in rheumatoid arthritis (RA) are unknown. We hypothesized that synovial tissue macrophages (STM), which persist in remission, contribute to joint homeostasis. We used single-cell transcriptomics to profile 32,000 STMs and identified phenotypic chan...

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Alivernini, S, MacDonald, L, Elmesmari, A, Finlay, S, Tolusso, B, Gigante, MR, Petricca, L, Di Mario, C, Bui, L, Perniola, S, Attar, M, Gessi, M, Fedele, AL, Chilaka, S, Sansom, S, Filer, A, McSharry, C, Millar, NL, Kirschner, K, Nerviani, A, Lewis, ML, Pitzalis, C, Clark, AL, Ferraccioli, G, Udalova, I, Buckley, C, Gremese, E, McInnes, IB, Otto, TD, Kurowska-Stolarska, M
التنسيق:	Journal article
اللغة:	English
منشور في:	Springer Nature 2020

Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis حسب Alivernini, S, MacDonald, L, Elmesmari, A, Finlay, S, Tolusso, B, Gigante, MR, Petricca, L, Di Mario, C, Bui, L, Perniola, S, Attar, M, Gessi, M, Fedele, AL, Chilaka, S, Somma, D, Sansom, SN, Filer, A, McSharry, C, Millar, NL, Kirschner, K, Nerviani, A, Lewis, MJ, Pitzalis, C, Clark, AR, Ferraccioli, G, Udalova, I, Buckley, CD, Gremese, E, McInnes, IB, Otto, TD, Kurowska-Stolarska, M

منشور في 2020

Journal article

Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis

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