A proposed new imaging pathway for patients with suspected lung cancer.

AIMS: PET-CT scans are routinely performed in patients with lung cancer after investigation by chest x-ray (CXR) and CT scan, when these have demonstrated potentially curable disease. If the majority of patients with lung cancer potentially suitable for curative treatment could be identified earlie...

Full description

Bibliographic Details
Main Authors: Macpherson, R, Benamore, R, Panakis, N, Sayeed, R, Breen, D, Bradley, K, Carter, R, Baldwin, D, Craig, J, Gleeson, F
Format: Journal article
Language:English
Published: 2012
_version_ 1797058399457771520
author Macpherson, R
Benamore, R
Panakis, N
Sayeed, R
Breen, D
Bradley, K
Carter, R
Baldwin, D
Craig, J
Gleeson, F
author_facet Macpherson, R
Benamore, R
Panakis, N
Sayeed, R
Breen, D
Bradley, K
Carter, R
Baldwin, D
Craig, J
Gleeson, F
author_sort Macpherson, R
collection OXFORD
description AIMS: PET-CT scans are routinely performed in patients with lung cancer after investigation by chest x-ray (CXR) and CT scan, when these have demonstrated potentially curable disease. If the majority of patients with lung cancer potentially suitable for curative treatment could be identified earlier in the diagnostic pathway on the basis of CXR findings they could be referred for PET-CT imaging without a prior CT scan. We investigated the clinical and financial implications of adopting such a strategy. MATERIALS AND METHODS: The details of 1187 patients referred with suspected lung cancer between July 2006 and August 2009 were analysed. The initial CXR and subsequent imaging of patients fit for curative treatment (Performance Status 0/1, FEV1 > 1.0) were reviewed (n = 251). The clinical and financial implications of referring patients for first line PET-CT if deemed potentially curable based on CXR findings were assessed. RESULTS: 107 of 1187 patients had potentially curable lung cancer on PS, lung function, CT and PET-CT. 96 of these 107 patients (90%) were correctly identified on CXR. 149 patients overall were diagnosed as potentially curable on CXR. Referring suitable patients for an immediate PET-CT scan resulted in a reduction in the time to complete staging investigations. CONCLUSIONS: Early PET-CT scanning for patients with suspected lung cancer, potentially suitable for curative therapy could result in more efficient staging with little additional cost.
first_indexed 2024-03-06T19:49:59Z
format Journal article
id oxford-uuid:23a45c7b-a6f8-411c-a028-a20d7f222327
institution University of Oxford
language English
last_indexed 2024-03-06T19:49:59Z
publishDate 2012
record_format dspace
spelling oxford-uuid:23a45c7b-a6f8-411c-a028-a20d7f2223272022-03-26T11:45:20ZA proposed new imaging pathway for patients with suspected lung cancer.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:23a45c7b-a6f8-411c-a028-a20d7f222327EnglishSymplectic Elements at Oxford2012Macpherson, RBenamore, RPanakis, NSayeed, RBreen, DBradley, KCarter, RBaldwin, DCraig, JGleeson, F AIMS: PET-CT scans are routinely performed in patients with lung cancer after investigation by chest x-ray (CXR) and CT scan, when these have demonstrated potentially curable disease. If the majority of patients with lung cancer potentially suitable for curative treatment could be identified earlier in the diagnostic pathway on the basis of CXR findings they could be referred for PET-CT imaging without a prior CT scan. We investigated the clinical and financial implications of adopting such a strategy. MATERIALS AND METHODS: The details of 1187 patients referred with suspected lung cancer between July 2006 and August 2009 were analysed. The initial CXR and subsequent imaging of patients fit for curative treatment (Performance Status 0/1, FEV1 > 1.0) were reviewed (n = 251). The clinical and financial implications of referring patients for first line PET-CT if deemed potentially curable based on CXR findings were assessed. RESULTS: 107 of 1187 patients had potentially curable lung cancer on PS, lung function, CT and PET-CT. 96 of these 107 patients (90%) were correctly identified on CXR. 149 patients overall were diagnosed as potentially curable on CXR. Referring suitable patients for an immediate PET-CT scan resulted in a reduction in the time to complete staging investigations. CONCLUSIONS: Early PET-CT scanning for patients with suspected lung cancer, potentially suitable for curative therapy could result in more efficient staging with little additional cost.
spellingShingle Macpherson, R
Benamore, R
Panakis, N
Sayeed, R
Breen, D
Bradley, K
Carter, R
Baldwin, D
Craig, J
Gleeson, F
A proposed new imaging pathway for patients with suspected lung cancer.
title A proposed new imaging pathway for patients with suspected lung cancer.
title_full A proposed new imaging pathway for patients with suspected lung cancer.
title_fullStr A proposed new imaging pathway for patients with suspected lung cancer.
title_full_unstemmed A proposed new imaging pathway for patients with suspected lung cancer.
title_short A proposed new imaging pathway for patients with suspected lung cancer.
title_sort proposed new imaging pathway for patients with suspected lung cancer
work_keys_str_mv AT macphersonr aproposednewimagingpathwayforpatientswithsuspectedlungcancer
AT benamorer aproposednewimagingpathwayforpatientswithsuspectedlungcancer
AT panakisn aproposednewimagingpathwayforpatientswithsuspectedlungcancer
AT sayeedr aproposednewimagingpathwayforpatientswithsuspectedlungcancer
AT breend aproposednewimagingpathwayforpatientswithsuspectedlungcancer
AT bradleyk aproposednewimagingpathwayforpatientswithsuspectedlungcancer
AT carterr aproposednewimagingpathwayforpatientswithsuspectedlungcancer
AT baldwind aproposednewimagingpathwayforpatientswithsuspectedlungcancer
AT craigj aproposednewimagingpathwayforpatientswithsuspectedlungcancer
AT gleesonf aproposednewimagingpathwayforpatientswithsuspectedlungcancer
AT macphersonr proposednewimagingpathwayforpatientswithsuspectedlungcancer
AT benamorer proposednewimagingpathwayforpatientswithsuspectedlungcancer
AT panakisn proposednewimagingpathwayforpatientswithsuspectedlungcancer
AT sayeedr proposednewimagingpathwayforpatientswithsuspectedlungcancer
AT breend proposednewimagingpathwayforpatientswithsuspectedlungcancer
AT bradleyk proposednewimagingpathwayforpatientswithsuspectedlungcancer
AT carterr proposednewimagingpathwayforpatientswithsuspectedlungcancer
AT baldwind proposednewimagingpathwayforpatientswithsuspectedlungcancer
AT craigj proposednewimagingpathwayforpatientswithsuspectedlungcancer
AT gleesonf proposednewimagingpathwayforpatientswithsuspectedlungcancer