Aurora A activates D-TACC-Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules.
Centrosomes are the dominant sites of microtubule (MT) assembly during mitosis in animal cells, but it is unclear how this is achieved. Transforming acidic coiled coil (TACC) proteins stabilize MTs during mitosis by recruiting Minispindles (Msps)/XMAP215 proteins to centrosomes. TACC proteins can be...
Κύριοι συγγραφείς: | Barros, T, Kinoshita, K, Hyman, A, Raff, J |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2005
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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Msps/XMAP215 interacts with the centrosomal protein D-TACC to regulate microtubule behaviour
ανά: Lee, M, κ.ά.
Έκδοση: (2001) -
Msps/XMAP215 interacts with the centrosomal protein D-TACC to regulate microtubule behaviour.
ανά: Lee, M, κ.ά.
Έκδοση: (2001) -
Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis.
ανά: Kinoshita, K, κ.ά.
Έκδοση: (2005) -
Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules.
ανά: Giet, R, κ.ά.
Έκδοση: (2002) -
Centrosomes and cancer: lessons from a TACC.
ανά: Raff, J
Έκδοση: (2002)