CD8 T cell response and evolutionary pressure to HIV-1 cryptic epitopes derived from antisense transcription.

CD8 T cell response and evolutionary pressure to HIV-1 cryptic epitopes derived from antisense transcription.

Retroviruses pack multiple genes into relatively small genomes by encoding several genes in the same genomic region with overlapping reading frames. Both sense and antisense HIV-1 transcripts contain open reading frames for known functional proteins as well as numerous alternative reading frames (AR...

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Detalles Bibliográficos
Main Authors: Bansal, A, Carlson, J, Yan, J, Akinsiku, O, Schaefer, M, Sabbaj, S, Bet, A, Levy, D, Heath, S, Tang, J, Kaslow, R, Walker, B, Ndung'u, T, Goulder, P, Heckerman, D, Hunter, E, Goepfert, P
Formato: Journal article
Idioma:English
Publicado: 2010

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