The prevalence of anxiety in general hospital inpatients: A systematic review and meta-analysis

Objective To determine the prevalence of anxiety in general hospital inpatients by conducting a systematic review and meta-analysis of all relevant published studies. Method We searched Ovid Medline, Ovid Embase and Ovid PsycINFO from inception to December 2020. We included studies of the prevalenc...

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Main Authors: Walker, J, van Niekerk, M, Hobbs, H, Toynbee, M, Magill, N, Bold, R, Hampsey, E, Harriss, E, Frost, C, Sharpe, M
Format: Journal article
Language:English
Published: Elsevier 2021
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author Walker, J
van Niekerk, M
Hobbs, H
Toynbee, M
Magill, N
Bold, R
Hampsey, E
Harriss, E
Frost, C
Sharpe, M
author_facet Walker, J
van Niekerk, M
Hobbs, H
Toynbee, M
Magill, N
Bold, R
Hampsey, E
Harriss, E
Frost, C
Sharpe, M
author_sort Walker, J
collection OXFORD
description Objective To determine the prevalence of anxiety in general hospital inpatients by conducting a systematic review and meta-analysis of all relevant published studies. Method We searched Ovid Medline, Ovid Embase and Ovid PsycINFO from inception to December 2020. We included studies of the prevalence of anxiety symptoms of clinically significant severity (using cut-off scores on rating scales) and of the prevalence of anxiety disorders (using diagnostic interviews) in general hospital inpatients. Two independent reviewers assessed articles and extracted data. The review is registered with PROSPERO, number CRD42020189722. Results We included 32 studies. Pooled prevalence estimates in random-effects meta-analyses were: anxiety symptoms 28% (95% CI 19% to 38%, 95% prediction interval 5% to 72%), any anxiety disorder 8% (95% CI 5% to 12%, 95% prediction interval 2% to 33%), panic disorder 3% (95% CI 2% to 4%, 95% prediction interval 1% to 8%), generalized anxiety disorder 5% (95% CI 3% to 8%, 95% prediction interval 1% to 23%). There was high heterogeneity in prevalence, little of which was explained in exploratory analyses of a limited number of potential determinants. Conclusion Anxiety symptoms of clinically significant severity affect more than one in four inpatients and anxiety disorders affect nearly one in ten.
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spelling oxford-uuid:23c34cc6-006d-4244-a7c3-0408d8d5167a2022-08-15T08:33:12ZThe prevalence of anxiety in general hospital inpatients: A systematic review and meta-analysisJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:23c34cc6-006d-4244-a7c3-0408d8d5167aEnglishSymplectic ElementsElsevier2021Walker, Jvan Niekerk, MHobbs, HToynbee, MMagill, NBold, RHampsey, EHarriss, EFrost, CSharpe, MObjective To determine the prevalence of anxiety in general hospital inpatients by conducting a systematic review and meta-analysis of all relevant published studies. Method We searched Ovid Medline, Ovid Embase and Ovid PsycINFO from inception to December 2020. We included studies of the prevalence of anxiety symptoms of clinically significant severity (using cut-off scores on rating scales) and of the prevalence of anxiety disorders (using diagnostic interviews) in general hospital inpatients. Two independent reviewers assessed articles and extracted data. The review is registered with PROSPERO, number CRD42020189722. Results We included 32 studies. Pooled prevalence estimates in random-effects meta-analyses were: anxiety symptoms 28% (95% CI 19% to 38%, 95% prediction interval 5% to 72%), any anxiety disorder 8% (95% CI 5% to 12%, 95% prediction interval 2% to 33%), panic disorder 3% (95% CI 2% to 4%, 95% prediction interval 1% to 8%), generalized anxiety disorder 5% (95% CI 3% to 8%, 95% prediction interval 1% to 23%). There was high heterogeneity in prevalence, little of which was explained in exploratory analyses of a limited number of potential determinants. Conclusion Anxiety symptoms of clinically significant severity affect more than one in four inpatients and anxiety disorders affect nearly one in ten.
spellingShingle Walker, J
van Niekerk, M
Hobbs, H
Toynbee, M
Magill, N
Bold, R
Hampsey, E
Harriss, E
Frost, C
Sharpe, M
The prevalence of anxiety in general hospital inpatients: A systematic review and meta-analysis
title The prevalence of anxiety in general hospital inpatients: A systematic review and meta-analysis
title_full The prevalence of anxiety in general hospital inpatients: A systematic review and meta-analysis
title_fullStr The prevalence of anxiety in general hospital inpatients: A systematic review and meta-analysis
title_full_unstemmed The prevalence of anxiety in general hospital inpatients: A systematic review and meta-analysis
title_short The prevalence of anxiety in general hospital inpatients: A systematic review and meta-analysis
title_sort prevalence of anxiety in general hospital inpatients a systematic review and meta analysis
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