Imaging DNA damage response (DDR) during oncogenesis
<p>Introduction: DNA damage repair (DDR) signalling is upregulated during tumorigenesis and acts as a p53-mediated block on proliferation. Expression of the DNA double strand break (DSB) repair protein, γH2AX, is induced by the activated kinases pATM or pATR during oncogenesis. Previously, we...
| Main Authors: | , , , |
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| פורמט: | Journal article |
| יצא לאור: |
American Association for Cancer Research
2013
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