Establishment of an aerosol challenge model of tuberculosis in rhesus macaques and an evaluation of endpoints for vaccine testing.

Establishment of an aerosol challenge model of tuberculosis in rhesus macaques and an evaluation of endpoints for vaccine testing.

The establishment of an aerosol challenge model in nonhuman primates (NHPs) for the testing of vaccines against Mycobacterium tuberculosis would assist the global effort to optimize novel vaccination strategies. The endpoints used in preclinical challenge studies to identify measures of disease burd...

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Những tác giả chính: Sharpe, SA, Mcshane, H, Dennis, M, Basaraba, R, Gleeson, F, Hall, G, McIntyre, A, Gooch, K, Clark, S, Beveridge, N, Nuth, E, White, A, Marriott, A, Dowall, S, Hill, A, Williams, A, Marsh, P
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2010

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