The role of declining ataxia-telangiectasia-mutated (ATM) function in oocyte aging

Despite the advances in the understanding of reproductive physiology, the mechanisms underlying ovarian aging are still not deciphered. Recent research found an association between impaired ATM-mediated DNA double-strand break (DSB) repair mechanisms and oocyte aging. However, direct evidence connec...

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Autori principali: Suzuki, R, Tan, X, Szymanska, KJ, Kubikova, N, Perez, CA, Wells, D, Oktay, KH
Natura: Journal article
Lingua:English
Pubblicazione: Springer Nature [academic journals on nature.com] 2024