Coeliac disease: an update for pathologists.
Coeliac disease is the manifestation of an immune hypersensitivity reaction towards gluten and related proteins, in genetically predisposed people. Although the precise pathogenesis of this condition remains to be fully elucidated, it is probably multifactorial in origin. The diagnosis of coeliac di...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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2006
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| _version_ | 1826263401158934528 |
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| author | Dickson, B Streutker, C Chetty, R |
| author_facet | Dickson, B Streutker, C Chetty, R |
| author_sort | Dickson, B |
| collection | OXFORD |
| description | Coeliac disease is the manifestation of an immune hypersensitivity reaction towards gluten and related proteins, in genetically predisposed people. Although the precise pathogenesis of this condition remains to be fully elucidated, it is probably multifactorial in origin. The diagnosis of coeliac disease has traditionally depended on intestinal biopsies alone; nowadays, the diagnosis has been expanded to include an array of serological markers. This review is intended to offer pathologists an update of the relevant history and immunopathology pertaining to coeliac disease and also to offer recommendations on the ongoing responsibilities of the pathologist in the diagnosis and reporting of coeliac disease. |
| first_indexed | 2024-03-06T19:51:10Z |
| format | Journal article |
| id | oxford-uuid:240644bb-3c6e-41e3-a883-35cc4a3e4b62 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T19:51:10Z |
| publishDate | 2006 |
| record_format | dspace |
| spelling | oxford-uuid:240644bb-3c6e-41e3-a883-35cc4a3e4b622022-03-26T11:47:37ZCoeliac disease: an update for pathologists.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:240644bb-3c6e-41e3-a883-35cc4a3e4b62EnglishSymplectic Elements at Oxford2006Dickson, BStreutker, CChetty, RCoeliac disease is the manifestation of an immune hypersensitivity reaction towards gluten and related proteins, in genetically predisposed people. Although the precise pathogenesis of this condition remains to be fully elucidated, it is probably multifactorial in origin. The diagnosis of coeliac disease has traditionally depended on intestinal biopsies alone; nowadays, the diagnosis has been expanded to include an array of serological markers. This review is intended to offer pathologists an update of the relevant history and immunopathology pertaining to coeliac disease and also to offer recommendations on the ongoing responsibilities of the pathologist in the diagnosis and reporting of coeliac disease. |
| spellingShingle | Dickson, B Streutker, C Chetty, R Coeliac disease: an update for pathologists. |
| title | Coeliac disease: an update for pathologists. |
| title_full | Coeliac disease: an update for pathologists. |
| title_fullStr | Coeliac disease: an update for pathologists. |
| title_full_unstemmed | Coeliac disease: an update for pathologists. |
| title_short | Coeliac disease: an update for pathologists. |
| title_sort | coeliac disease an update for pathologists |
| work_keys_str_mv | AT dicksonb coeliacdiseaseanupdateforpathologists AT streutkerc coeliacdiseaseanupdateforpathologists AT chettyr coeliacdiseaseanupdateforpathologists |