Persistence of collagen type II-specific T-cell clones in the synovial membrane of a patient with rheumatoid arthritis.
Rheumatoid arthritis is an autoimmune disease characterized by T-cell infiltration of the synovium of joints. Analysis of the phenotype and antigen specificity of the infiltrating cells may thus provide insight into the pathogenesis of rheumatoid arthritis. T cells were cloned with interleukin 2, a...
Main Authors: | Londei, M, Savill, C, Verhoef, A, Brennan, F, Leech, Z, Duance, V, Maini, R, Feldmann, M |
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Format: | Journal article |
Language: | English |
Published: |
1989
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