TGF- 2signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution

The thymus constitutes the primary lymphoid organ responsible for the generation of naive T cells. Its stromal compartment is largely composed of a scaffold of different subsets of epithelial cells that provide soluble and membrane-bound molecules essential for thymocyte maturation and selection. Wi...

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Detalhes bibliográficos
Principais autores: Hauri-Hohl, M, Zuklys, S, Keller, M, Jeker, LT, Barthlott, T, Moon, A, Roes, J, Holländer, G
Formato: Journal article
Idioma:English
Publicado em: 2008