A meta-analysis of interleukin-6 promoter polymorphisms on risk of hip and knee osteoarthritis.

A meta-analysis of interleukin-6 promoter polymorphisms on risk of hip and knee osteoarthritis.

OBJECTIVE: Interleukin-6 is a pro-inflammatory cytokine involved in the pathogenesis of osteoarthritis (OA). We investigated the role of two single nucleotide polymorphisms (SNPs) mapping to the promoter of the IL-6 gene on genetic susceptibility to hip and knee OA. METHODS: The -174G/C (rs1800795)...

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Bibliographic Details
Main Authors:	Valdes, A, Arden, N, Tamm, A, Kisand, K, Doherty, S, Pola, E, Cooper, C, Muir, K, Kerna, I, Hart, D, O'Neil, F, Zhang, W, Spector, T, Maciewicz, R, Doherty, M
Format:	Journal article
Language:	English
Published:	2010

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