A historical survey of key epidemiological studies of ionizing radiation exposure

In this article we review the history of key epidemiological studies of populations exposed to ionizing radiation. We highlight historical and recent findings regarding radiation-associated risks for incidence and mortality of cancer and non-cancer outcomes with emphasis on study design and methods...

Full description

Bibliographic Details
Main Authors: Little, MP, Bazyka, D, Gonzalez, ABD, Brenner, AV, Chumak, VV, Cullings, H, Daniels, RD, French, B, Grant, E, Hamada, N, Hauptmann, M, Kendall, GM, Laurier, D, Lee, C, Lee, WJ, Linet, MS, Mabuchi, K, Morton, LM, Muirhead, CR, Preston, DL, Rajaraman, P, Richardson, DB, Sakata, R, Samet, JM, Simon, SL, Sugiyama, H, Wakeford, R, Zablotska, LB
Format: Journal article
Language:English
Published: BioOne 2024
_version_ 1826314255136194560
author Little, MP
Bazyka, D
Gonzalez, ABD
Brenner, AV
Chumak, VV
Cullings, H
Daniels, RD
French, B
Grant, E
Hamada, N
Hauptmann, M
Kendall, GM
Laurier, D
Lee, C
Lee, WJ
Linet, MS
Mabuchi, K
Morton, LM
Muirhead, CR
Preston, DL
Rajaraman, P
Richardson, DB
Sakata, R
Samet, JM
Simon, SL
Sugiyama, H
Wakeford, R
Zablotska, LB
author_facet Little, MP
Bazyka, D
Gonzalez, ABD
Brenner, AV
Chumak, VV
Cullings, H
Daniels, RD
French, B
Grant, E
Hamada, N
Hauptmann, M
Kendall, GM
Laurier, D
Lee, C
Lee, WJ
Linet, MS
Mabuchi, K
Morton, LM
Muirhead, CR
Preston, DL
Rajaraman, P
Richardson, DB
Sakata, R
Samet, JM
Simon, SL
Sugiyama, H
Wakeford, R
Zablotska, LB
author_sort Little, MP
collection OXFORD
description In this article we review the history of key epidemiological studies of populations exposed to ionizing radiation. We highlight historical and recent findings regarding radiation-associated risks for incidence and mortality of cancer and non-cancer outcomes with emphasis on study design and methods of exposure assessment and dose estimation along with brief consideration of sources of bias for a few of the more important studies. We examine the findings from the epidemiological studies of the Japanese atomic bomb survivors, persons exposed to radiation for diagnostic or therapeutic purposes, those exposed to environmental sources including Chornobyl and other reactor accidents, and occupationally exposed cohorts. We also summarize results of pooled studies. These summaries are necessarily brief, but we provide references to more detailed information. We discuss possible future directions of study, to include assessment of susceptible populations, and possible new populations, data sources, study designs and methods of analysis.
first_indexed 2024-09-25T04:29:40Z
format Journal article
id oxford-uuid:24249b08-8120-4593-a985-c799aafa6623
institution University of Oxford
language English
last_indexed 2024-09-25T04:29:40Z
publishDate 2024
publisher BioOne
record_format dspace
spelling oxford-uuid:24249b08-8120-4593-a985-c799aafa66232024-08-27T15:36:50ZA historical survey of key epidemiological studies of ionizing radiation exposureJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:24249b08-8120-4593-a985-c799aafa6623EnglishSymplectic ElementsBioOne2024Little, MPBazyka, DGonzalez, ABDBrenner, AVChumak, VVCullings, HDaniels, RDFrench, BGrant, EHamada, NHauptmann, MKendall, GMLaurier, DLee, CLee, WJLinet, MSMabuchi, KMorton, LMMuirhead, CRPreston, DLRajaraman, PRichardson, DBSakata, RSamet, JMSimon, SLSugiyama, HWakeford, RZablotska, LBIn this article we review the history of key epidemiological studies of populations exposed to ionizing radiation. We highlight historical and recent findings regarding radiation-associated risks for incidence and mortality of cancer and non-cancer outcomes with emphasis on study design and methods of exposure assessment and dose estimation along with brief consideration of sources of bias for a few of the more important studies. We examine the findings from the epidemiological studies of the Japanese atomic bomb survivors, persons exposed to radiation for diagnostic or therapeutic purposes, those exposed to environmental sources including Chornobyl and other reactor accidents, and occupationally exposed cohorts. We also summarize results of pooled studies. These summaries are necessarily brief, but we provide references to more detailed information. We discuss possible future directions of study, to include assessment of susceptible populations, and possible new populations, data sources, study designs and methods of analysis.
spellingShingle Little, MP
Bazyka, D
Gonzalez, ABD
Brenner, AV
Chumak, VV
Cullings, H
Daniels, RD
French, B
Grant, E
Hamada, N
Hauptmann, M
Kendall, GM
Laurier, D
Lee, C
Lee, WJ
Linet, MS
Mabuchi, K
Morton, LM
Muirhead, CR
Preston, DL
Rajaraman, P
Richardson, DB
Sakata, R
Samet, JM
Simon, SL
Sugiyama, H
Wakeford, R
Zablotska, LB
A historical survey of key epidemiological studies of ionizing radiation exposure
title A historical survey of key epidemiological studies of ionizing radiation exposure
title_full A historical survey of key epidemiological studies of ionizing radiation exposure
title_fullStr A historical survey of key epidemiological studies of ionizing radiation exposure
title_full_unstemmed A historical survey of key epidemiological studies of ionizing radiation exposure
title_short A historical survey of key epidemiological studies of ionizing radiation exposure
title_sort historical survey of key epidemiological studies of ionizing radiation exposure
work_keys_str_mv AT littlemp ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT bazykad ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT gonzalezabd ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT brennerav ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT chumakvv ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT cullingsh ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT danielsrd ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT frenchb ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT grante ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT hamadan ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT hauptmannm ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT kendallgm ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT laurierd ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT leec ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT leewj ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT linetms ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT mabuchik ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT mortonlm ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT muirheadcr ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT prestondl ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT rajaramanp ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT richardsondb ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT sakatar ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT sametjm ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT simonsl ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT sugiyamah ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT wakefordr ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT zablotskalb ahistoricalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT littlemp historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT bazykad historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT gonzalezabd historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT brennerav historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT chumakvv historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT cullingsh historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT danielsrd historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT frenchb historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT grante historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT hamadan historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT hauptmannm historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT kendallgm historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT laurierd historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT leec historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT leewj historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT linetms historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT mabuchik historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT mortonlm historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT muirheadcr historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT prestondl historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT rajaramanp historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT richardsondb historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT sakatar historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT sametjm historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT simonsl historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT sugiyamah historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT wakefordr historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure
AT zablotskalb historicalsurveyofkeyepidemiologicalstudiesofionizingradiationexposure