Asymmetric synthesis of a highly functionalized beta-amino acid: the key amino acid of sperabillins B and D

The asymmetric synthesis of the highly functionalized (3R,5R,6R)-3,6-diamino-5-hydroxyheptanoic acid, the key amino acid fragment of sperabillins B and D, was achieved by an asymmetric Michael addition of lithium (R)-(α-methylbenzyl)allylamide 10 to (E,E)-2,5-heptadienoate establishing the C-3 stere...

Полное описание

Библиографические подробности
Главные авторы: Davies, S, Ichihara, O
Формат: Journal article
Язык:English
Опубликовано: 1999