Synthesis and recycling of tetrahydrobiopterin in endothelial function and vascular disease.
Nitric oxide, generated by the nitric oxide synthase (NOS) enzymes, plays pivotal roles in cardiovascular homeostasis and in the pathogenesis of cardiovascular disease. The NOS cofactor, tetrahydrobiopterin (BH4), is an important regulator of NOS function, since BH4 is required to maintain enzymatic...
Main Authors: | Crabtree, M, Channon, K |
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פורמט: | Journal article |
שפה: | English |
יצא לאור: |
2011
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פריטים דומים
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Synthesis and recycling of tetrahydrobiopterin in endothelial function and vascular disease
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Tetrahydrobiopterin: a vascular redox target to improve endothelial function.
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Tetrahydrobiopterin: regulator of endothelial nitric oxide synthase in vascular disease.
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A key role for tetrahydrobiopterin-dependent endothelial NOS regulation in vascular resistance arteries: studies in endothelial cell tetrahydrobiopterin-deficient mice
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Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease.
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