Cholera toxin enhances vaccine-induced protection against Mycobacterium tuberculosis challenge in mice
Interleukin (IL)-17 is emerging as an important cytokine in vaccine-induced protection against tuberculosis disease in animal models. Here we show that compared to parenteral delivery, BCG delivered mucosally enhances cytokine production, including interferon gamma and IL-17, in the lungs. Furthermo...
Hauptverfasser: | Griffiths, K, Stylianou, E, Poyntz, H, Betts, G, Fletcher, H, McShane, H |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
Public Library of Science
2013
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