Cholera toxin enhances vaccine-induced protection against Mycobacterium tuberculosis challenge in mice

Interleukin (IL)-17 is emerging as an important cytokine in vaccine-induced protection against tuberculosis disease in animal models. Here we show that compared to parenteral delivery, BCG delivered mucosally enhances cytokine production, including interferon gamma and IL-17, in the lungs. Furthermo...

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Những tác giả chính: Griffiths, K, Stylianou, E, Poyntz, H, Betts, G, Fletcher, H, McShane, H
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Public Library of Science 2013