Selective inhibition of factor inhibiting hypoxia-inducible factor.

A set of four non-heme iron(II) and 2-oxoglutarate-dependent enzymes catalyze the post-translational modification of a transcription factor, hypoxia inducible factor (HIF), that mediates the hypoxic response in animals. Hydroxylation of HIF both causes its degradation and limits its activity. We des...

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Những tác giả chính: McDonough, M, McNeill, L, Tilliet, M, Papamicaël, C, Chen, Q, Banerji, B, Hewitson, K, Schofield, C
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2005

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