HIV-1 glycan density drives the persistence of the mannose patch within an infected individual
The HIV envelope (Env) is extensively modified with host-derived N-linked glycans. The high density of glycosylation on the viral spike limits enzymatic processing resulting in numerous under-processed oligomannose-type glycans. This extensive glycosylation not only shields conserved regions of t...
| Main Authors: | , , , , , , , , |
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| Format: | Journal article |
| Published: |
American Society for Microbiology
2016
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