Lesions induced in DNA by ultraviolet light are repaired at the nuclear cage.

In mammalian cells, S-phase DNA synthesis occurs at sites fixed to a sub-nuclear structure, the nuclear matrix or cage. This is an ordered network of non-histone proteins, which maintains its essential morphology even in the absence of DNA. We show here that unscheduled DNA synthesis following expos...

Descrición completa

Detalles Bibliográficos
Main Authors: McCready, S, Cook, P
Formato: Journal article
Idioma:English
Publicado: 1984