Lesions induced in DNA by ultraviolet light are repaired at the nuclear cage.
In mammalian cells, S-phase DNA synthesis occurs at sites fixed to a sub-nuclear structure, the nuclear matrix or cage. This is an ordered network of non-histone proteins, which maintains its essential morphology even in the absence of DNA. We show here that unscheduled DNA synthesis following expos...
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
1984
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