Electrocatalytic detection of thiols using an edge plane pyrolytic graphite electrode.
The first example of using an edge plane pyrolytic graphite electrode in electroanalysis is reported as the determination of homocysteine, N-acetylcysteine, cysteine and glutathione is studied. The response of the electrode in the direct oxidation of thiol moieties is explored and found to be electr...
| Autores principales: | , , |
|---|---|
| Formato: | Journal article |
| Lenguaje: | English |
| Publicado: |
2004
|
| _version_ | 1826263489953398784 |
|---|---|
| author | Moore, R Banks, C Compton, R |
| author_facet | Moore, R Banks, C Compton, R |
| author_sort | Moore, R |
| collection | OXFORD |
| description | The first example of using an edge plane pyrolytic graphite electrode in electroanalysis is reported as the determination of homocysteine, N-acetylcysteine, cysteine and glutathione is studied. The response of the electrode in the direct oxidation of thiol moieties is explored and found to be electrocatalytic producing a reduction in the overpotential while having enhanced signal-to-noise characteristics compared to glassy carbon and basal plane pyrolytic graphite electrodes. The effectiveness of the methodology is examined in the determination of cysteine species in a growth tissue media that contains a high number of common biological interferences. The advantageous properties of this electrode for thiol determination lie in its excellent catalytic activity, sensitivity and simplicity. |
| first_indexed | 2024-03-06T19:52:35Z |
| format | Journal article |
| id | oxford-uuid:2473b204-aa4a-4c15-8514-ba022fe33305 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T19:52:35Z |
| publishDate | 2004 |
| record_format | dspace |
| spelling | oxford-uuid:2473b204-aa4a-4c15-8514-ba022fe333052022-03-26T11:50:09ZElectrocatalytic detection of thiols using an edge plane pyrolytic graphite electrode.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:2473b204-aa4a-4c15-8514-ba022fe33305EnglishSymplectic Elements at Oxford2004Moore, RBanks, CCompton, RThe first example of using an edge plane pyrolytic graphite electrode in electroanalysis is reported as the determination of homocysteine, N-acetylcysteine, cysteine and glutathione is studied. The response of the electrode in the direct oxidation of thiol moieties is explored and found to be electrocatalytic producing a reduction in the overpotential while having enhanced signal-to-noise characteristics compared to glassy carbon and basal plane pyrolytic graphite electrodes. The effectiveness of the methodology is examined in the determination of cysteine species in a growth tissue media that contains a high number of common biological interferences. The advantageous properties of this electrode for thiol determination lie in its excellent catalytic activity, sensitivity and simplicity. |
| spellingShingle | Moore, R Banks, C Compton, R Electrocatalytic detection of thiols using an edge plane pyrolytic graphite electrode. |
| title | Electrocatalytic detection of thiols using an edge plane pyrolytic graphite electrode. |
| title_full | Electrocatalytic detection of thiols using an edge plane pyrolytic graphite electrode. |
| title_fullStr | Electrocatalytic detection of thiols using an edge plane pyrolytic graphite electrode. |
| title_full_unstemmed | Electrocatalytic detection of thiols using an edge plane pyrolytic graphite electrode. |
| title_short | Electrocatalytic detection of thiols using an edge plane pyrolytic graphite electrode. |
| title_sort | electrocatalytic detection of thiols using an edge plane pyrolytic graphite electrode |
| work_keys_str_mv | AT moorer electrocatalyticdetectionofthiolsusinganedgeplanepyrolyticgraphiteelectrode AT banksc electrocatalyticdetectionofthiolsusinganedgeplanepyrolyticgraphiteelectrode AT comptonr electrocatalyticdetectionofthiolsusinganedgeplanepyrolyticgraphiteelectrode |