Probing novel epitopes on the Plasmodium falciparum circumsporozoite protein for vaccine development

RTS,S and R21 are the only vaccines recommended by the WHO to protect children from Plasmodium falciparum (Pf) clinical malaria. Both vaccines target the Pf sporozoite surface protein circumsporozoite protein (CSP). Recent studies showed that human antibodies neutralize Pf sporozoites most efficient...

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Bibliografski detalji
Glavni autori: Krenger, PS, Roques, M, Vogt, AS, Pardini, A, Rothen, DA, Balke, I, Schnider, ST, Mohsen, MO, Heussler, VT, Zeltins, A, Bachmann, MF
Format: Journal article
Jezik:English
Izdano: Nature Research 2024