The immune microenvironment of HPV-negative oral squamous cell carcinoma from never-smokers and never-drinkers patients suggests higher clinical benefit of IDO1 and PD1/PD-L1 blockade.

The immune microenvironment of HPV-negative oral squamous cell carcinoma from never-smokers and never-drinkers patients suggests higher clinical benefit of IDO1 and PD1/PD-L1 blockade.

<h4>Background</h4> <p>Never-smokers and never-drinkers patients (NSND) suffering from oral squamous cell carcinoma (OSCC) are epidemiologically different from smokers drinkers (SD). We therefore hypothesized that they harbored distinct targetable molecular alterations.</p>...

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Bibliographic Details
Main Authors: Foy, J, Bertolus, C, Michallet, M, Deneuve, S, Incitti, R, Bendriss-Vermare, N, Albaret, M, Ortiz-Cuaran, S, Thomas, E, Colombe, A, Py, C, Gadot, N, Michot, J, Fayette, J, Viari, A, Van den Eynde, B, Goudot, P, Devouassoux-Shisheboran, M, Puisieux, A, Caux, C, Zrounba, P, Lantuejoul, S, Saintigny, P
Format: Journal article
Language:English
Published: Oxford University Press 2017

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