Experimental characterization of disordered and ordered aggregates populated during the process of amyloid fibril formation.

Experimental characterization of disordered and ordered aggregates populated during the process of amyloid fibril formation.

Recent experimental evidence points to intermediates populated during the process of amyloid fibril formation as the toxic moieties primarily responsible for the development of increasingly common disorders such as Alzheimer's disease and type II diabetes. We describe here the application of a...

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Bibliografiske detaljer
Main Authors:	Carulla, N, Zhou, M, Arimon, M, Gairí, M, Giralt, E, Robinson, C, Dobson, C
Format:	Journal article
Sprog:	English
Udgivet:	2009

Lignende værker

Structure and intermolecular dynamics of aggregates populated during amyloid fibril formation studied by hydrogen/deuterium exchange.
af: Carulla, N, et al.
Udgivet: (2010)

Molecular recycling within amyloid fibrils.
af: Carulla, N, et al.
Udgivet: (2005)

Amyloid fibril formation by an SH3 domain.
af: Guijarro, J, et al.
Udgivet: (1998)

Formation of insulin amyloid fibrils followed by FTIR simultaneously with CD and electron microscopy.
af: Bouchard, M, et al.
Udgivet: (2000)

A beta 40 and A beta 42 Amyloid Fibrils Exhibit Distinct Molecular Recycling Properties
af: Sanchez, L, et al.
Udgivet: (2011)

Aβ40 and Aβ42 amyloid fibrils exhibit distinct molecular recycling properties.
af: Sánchez, L, et al.
Udgivet: (2011)

BIOT 243-Biophysical study of the aggregation of human lysozyme into amyloid fibrils
af: Dhulesia, A, et al.
Udgivet: (2008)

Amyloid fibril formation by a helical cytochrome.
af: Pertinhez, T, et al.
Udgivet: (2001)

Characterization of the oligomeric states of insulin in self-assembly and amyloid fibril formation by mass spectrometry.
af: Nettleton, E, et al.
Udgivet: (2000)

The protofilament structure of insulin amyloid fibrils.
af: Jiménez, J, et al.
Udgivet: (2002)

Prediction of fibril formation by early-stage amyloid peptide aggregation
af: Jiaojiao Hu, et al.
Udgivet: (2020-04-01)

Insights into amyloid fibril formation from mass spectrometry.
af: Caddy, G, et al.
Udgivet: (2006)

Amyloid fibril formation by the SCR3 domain of human complement receptor 1.
af: Pertinhez, T, et al.
Udgivet: (2000)

Observation of sequence specificity in the seeding of protein amyloid fibrils.
af: Krebs, MR, et al.
Udgivet: (2004)

A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme.
af: Dumoulin, M, et al.
Udgivet: (2003)

Cytochrome display on amyloid fibrils.
af: Baldwin, A, et al.
Udgivet: (2006)

Phospholipids as inhibitors of amyloid fibril formation
af: K. O. Vus, et al.
Udgivet: (2016-11-01)

Formation and seeding of amyloid fibrils from wild-type hen lysozyme and a peptide fragment from the beta-domain.
af: Krebs, MR, et al.
Udgivet: (2000)

A simple lattice model that captures protein folding, aggregation and amyloid formation.
af: Sanne Abeln, et al.
Udgivet: (2014-01-01)

A generic mechanism of emergence of amyloid protofilaments from disordered oligomeric aggregates.
af: Stefan Auer, et al.
Udgivet: (2008-11-01)

Trehalose Effect on The Aggregation of Model Proteins into Amyloid Fibrils
af: Eleonora Mari, et al.
Udgivet: (2020-05-01)

Simultaneous measurement of amyloid fibril formation by dynamic light scattering and fluorescence reveals complex aggregation kinetics.
af: Aaron M Streets, et al.
Udgivet: (2013-01-01)

Formation of soluble amyloid oligomers and amyloid fibrils by the multifunctional protein vitronectin
af: Langen Ralf, et al.
Udgivet: (2008-10-01)

Amyloid fibril formation in Alzheimer's disease
af: Jarrett, Joseph Timothy
Udgivet: (2012)

Supersaturation-Dependent Formation of Amyloid Fibrils
af: Yuji Goto, et al.
Udgivet: (2022-07-01)

Effect of surfaces on amyloid fibril formation.
af: Bradley Moores, et al.
Udgivet: (2011-01-01)

Amyloid fibril formation is suppressed in microgravity
af: Hiroaki Matsushita, et al.
Udgivet: (2021-03-01)

Higher Order Amyloid Fibril Structure by MAS NMR and DNP Spectroscopy
af: Debelouchina, Galia Tzvetanova, et al.
Udgivet: (2015)

Perturbation of the stability of amyloid fibrils through alteration of electrostatic interactions.
af: Shammas, S, et al.
Udgivet: (2011)

Tyrosine Rotamer States in Beta Amyloid: Signatures of Aggregation and Fibrillation
af: Onorio Mancini, et al.
Udgivet: (2018-11-01)

Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis.
af: Booth, DR, et al.
Udgivet: (1997)

An atlas of amyloid aggregation: the impact of substitutions, insertions, deletions and truncations on amyloid beta fibril nucleation
af: Mireia Seuma, et al.
Udgivet: (2022-11-01)

Suppression of amyloid fibril formation by UV irradiation
af: Hiroaki Matsushita, et al.
Udgivet: (2022-12-01)

Influence of Aluminium and EGCG on Fibrillation and Aggregation of Human Islet Amyloid Polypeptide
af: Zhi-Xue Xu, et al.
Udgivet: (2016-01-01)

Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity
af: Arun Upadhyay, et al.
Udgivet: (2023-09-01)

Effects of Protein Corona on IAPP Amyloid Aggregation, Fibril Remodelling, and Cytotoxicity
af: Emily H. Pilkington, et al.
Udgivet: (2017-05-01)

Thioflavin T as an amyloid dye: fibril quantification, optimal concentration and effect on aggregation
af: Christine Xue, et al.
Udgivet: (2017-01-01)

Ultrastructural organization of amyloid fibrils by atomic force microscopy.
af: Chamberlain, A, et al.
Udgivet: (2000)

A role for amyloid in cell aggregation and biofilm formation.
af: Melissa C Garcia, et al.
Udgivet: (2011-03-01)

A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.
af: De Genst, E, et al.
Udgivet: (2013)