Lysyl oxidase‐like 2 is a regulator of angiogenesis through modulation of endothelial‐to‐mesenchymal transition
Lysyl oxidase‐like 2 (LOXL2) belongs to the family of lysyl oxidases, and as such promotes crosslinking of collagens and elastin by oxidative deamination of lysine residues. In endothelial cells (ECs), LOXL2 is involved in crosslinking and scaffolding of collagen IV. Additionally, several reports ha...
Main Authors: | De Jong, O, Van Der Waals, L, Kools, F, Verhaar, M, Van Balkom, B |
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Format: | Journal article |
Published: |
Wiley
2018
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