Neuropilin-2 expression affects the increased vascularization and is a prognostic factor in osteosarcoma.
Osteosarcoma is a malignant bone tumor characterized by hypervascularity. Neuropilins (NRPs), which is expressed by human tumor cells, is known to be a potent receptor for vascular endothelial growth factor (VEGF). We examined NRPs mRNA expression in 30 osteosarcomas. The osteosarcomas with NRP2 exp...
Main Authors: | Handa, A, Tokunaga, T, Tsuchida, T, Lee, Y, Kijima, H, Yamazaki, H, Ueyama, Y, Fukuda, H, Nakamura, M |
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Format: | Journal article |
Language: | English |
Published: |
2000
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