Studies on the biomimetic synthesis of the manzamine alkaloids
The biomimetic synthesis of the manzamine-related alkaloid keramaphidin B is described. The key intramolecular Diels-Alder reaction proposed in the Baldwin and Whitehead hypothesis is demonstrated. An investigation of the modified biomimetic hypothesis proposed by Marazano et al. is also reported. F...
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1999
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| _version_ | 1826263681476853760 |
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| author | Baldwin, J Claridge, T Culshaw, A Heupel, F Lee, V Spring, DR Whitehead, R |
| author_facet | Baldwin, J Claridge, T Culshaw, A Heupel, F Lee, V Spring, DR Whitehead, R |
| author_sort | Baldwin, J |
| collection | OXFORD |
| description | The biomimetic synthesis of the manzamine-related alkaloid keramaphidin B is described. The key intramolecular Diels-Alder reaction proposed in the Baldwin and Whitehead hypothesis is demonstrated. An investigation of the modified biomimetic hypothesis proposed by Marazano et al. is also reported. Finally, an alternative synthesis of keramaphidin B by Grubbs methathesis is presented. |
| first_indexed | 2024-03-06T19:55:41Z |
| format | Journal article |
| id | oxford-uuid:257fab8c-9a21-45ec-95ad-9ad3e0d1957e |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T19:55:41Z |
| publishDate | 1999 |
| record_format | dspace |
| spelling | oxford-uuid:257fab8c-9a21-45ec-95ad-9ad3e0d1957e2022-03-26T11:55:57ZStudies on the biomimetic synthesis of the manzamine alkaloidsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:257fab8c-9a21-45ec-95ad-9ad3e0d1957eEnglishSymplectic Elements at Oxford1999Baldwin, JClaridge, TCulshaw, AHeupel, FLee, VSpring, DRWhitehead, RThe biomimetic synthesis of the manzamine-related alkaloid keramaphidin B is described. The key intramolecular Diels-Alder reaction proposed in the Baldwin and Whitehead hypothesis is demonstrated. An investigation of the modified biomimetic hypothesis proposed by Marazano et al. is also reported. Finally, an alternative synthesis of keramaphidin B by Grubbs methathesis is presented. |
| spellingShingle | Baldwin, J Claridge, T Culshaw, A Heupel, F Lee, V Spring, DR Whitehead, R Studies on the biomimetic synthesis of the manzamine alkaloids |
| title | Studies on the biomimetic synthesis of the manzamine alkaloids |
| title_full | Studies on the biomimetic synthesis of the manzamine alkaloids |
| title_fullStr | Studies on the biomimetic synthesis of the manzamine alkaloids |
| title_full_unstemmed | Studies on the biomimetic synthesis of the manzamine alkaloids |
| title_short | Studies on the biomimetic synthesis of the manzamine alkaloids |
| title_sort | studies on the biomimetic synthesis of the manzamine alkaloids |
| work_keys_str_mv | AT baldwinj studiesonthebiomimeticsynthesisofthemanzaminealkaloids AT claridget studiesonthebiomimeticsynthesisofthemanzaminealkaloids AT culshawa studiesonthebiomimeticsynthesisofthemanzaminealkaloids AT heupelf studiesonthebiomimeticsynthesisofthemanzaminealkaloids AT leev studiesonthebiomimeticsynthesisofthemanzaminealkaloids AT springdr studiesonthebiomimeticsynthesisofthemanzaminealkaloids AT whiteheadr studiesonthebiomimeticsynthesisofthemanzaminealkaloids |