11Beta-hydroxysteroid dehydrogenase type 1 in human disease: a novel therapeutic target.

Patients with cortisol excess, Cushing's syndrome, develop a classical phenotype characterized by central obesity, hypertension, and increased cardiovascular mortality. Whilst this observation points to the importance of glucocorticoids, circulating cortisol excess is rare and does not explain...

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Tác giả chính: Tomlinson, J
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2005