Tropism of engineered and evolved recombinant AAV serotypes in the rd1 mouse and ex vivo primate retina

Tropism of engineered and evolved recombinant AAV serotypes in the rd1 mouse and ex vivo primate retina

There is much debate on the adeno-associated virus (AAV) serotype that best targets specific retinal cell types and the route of surgical delivery — intravitreal or subretinal. This study compared three of the most efficacious AAV vectors known to date in a mouse model of retinal degeneration (rd1 m...

書誌詳細
主要な著者:	Hickey, DG, Edwards, TL, Barnard, AR, Singh, MS, de Silva, SR, McClements, ME, Flannery, JG, Hankins, MW, Maclaren, RE
フォーマット:	Journal article
出版事項:	Nature Publishing Group 2017

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