Understanding the origins of remote asymmetric induction in the boron aldol reactions of beta-alkoxy methyl ketones.
We report theoretical studies into the remote 1,5-stereoinduction shown by certain types of beta-alkoxy methyl ketones in boron-mediated aldol reactions with achiral aldehydes. For a range of common alkoxy groups, our calculations are in excellent agreement with experimentally observed diastereosele...
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Bibliographic Details
| Main Authors: |
Paton, R,
Goodman, J |
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| Format: | Journal article
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| Language: | English |
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| Published: |
2006
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