Bullous pemphigoid and multiple sclerosis: a report of three cases and review of the literature.

Three patients with longstanding multiple sclerosis (MS) who developed bullous pemphigoid (BP) are reported. All patients had immunological features of typical BP as determined by immunofluorescence and Western immunoblotting studies. The clinical features, however, differed from those observed in t...

Full description

Bibliographic Details
Main Authors: Kirtschig, G, Walkden, V, Venning, V, Wojnarowska, F
Format: Journal article
Language:English
Published: 1995
_version_ 1797058871935631360
author Kirtschig, G
Walkden, V
Venning, V
Wojnarowska, F
author_facet Kirtschig, G
Walkden, V
Venning, V
Wojnarowska, F
author_sort Kirtschig, G
collection OXFORD
description Three patients with longstanding multiple sclerosis (MS) who developed bullous pemphigoid (BP) are reported. All patients had immunological features of typical BP as determined by immunofluorescence and Western immunoblotting studies. The clinical features, however, differed from those observed in typical BP. In two the BP started near an indwelling catheter and two had striking involvement of the soles. None of our patients, or a further nine cases reported in the literature, had mucous membrane involvement. In MS patients BP appears to develop at a younger age. Multiple drugs were taken by the MS patients; these, however, appear not to play a role in triggering their BP. The course of BP in patients with MS is moderate, although the majority require systemic treatment.
first_indexed 2024-03-06T19:56:29Z
format Journal article
id oxford-uuid:25c702c4-421c-472e-8a15-d9e4fe0f0e66
institution University of Oxford
language English
last_indexed 2024-03-06T19:56:29Z
publishDate 1995
record_format dspace
spelling oxford-uuid:25c702c4-421c-472e-8a15-d9e4fe0f0e662022-03-26T11:57:26ZBullous pemphigoid and multiple sclerosis: a report of three cases and review of the literature.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:25c702c4-421c-472e-8a15-d9e4fe0f0e66EnglishSymplectic Elements at Oxford1995Kirtschig, GWalkden, VVenning, VWojnarowska, FThree patients with longstanding multiple sclerosis (MS) who developed bullous pemphigoid (BP) are reported. All patients had immunological features of typical BP as determined by immunofluorescence and Western immunoblotting studies. The clinical features, however, differed from those observed in typical BP. In two the BP started near an indwelling catheter and two had striking involvement of the soles. None of our patients, or a further nine cases reported in the literature, had mucous membrane involvement. In MS patients BP appears to develop at a younger age. Multiple drugs were taken by the MS patients; these, however, appear not to play a role in triggering their BP. The course of BP in patients with MS is moderate, although the majority require systemic treatment.
spellingShingle Kirtschig, G
Walkden, V
Venning, V
Wojnarowska, F
Bullous pemphigoid and multiple sclerosis: a report of three cases and review of the literature.
title Bullous pemphigoid and multiple sclerosis: a report of three cases and review of the literature.
title_full Bullous pemphigoid and multiple sclerosis: a report of three cases and review of the literature.
title_fullStr Bullous pemphigoid and multiple sclerosis: a report of three cases and review of the literature.
title_full_unstemmed Bullous pemphigoid and multiple sclerosis: a report of three cases and review of the literature.
title_short Bullous pemphigoid and multiple sclerosis: a report of three cases and review of the literature.
title_sort bullous pemphigoid and multiple sclerosis a report of three cases and review of the literature
work_keys_str_mv AT kirtschigg bullouspemphigoidandmultiplesclerosisareportofthreecasesandreviewoftheliterature
AT walkdenv bullouspemphigoidandmultiplesclerosisareportofthreecasesandreviewoftheliterature
AT venningv bullouspemphigoidandmultiplesclerosisareportofthreecasesandreviewoftheliterature
AT wojnarowskaf bullouspemphigoidandmultiplesclerosisareportofthreecasesandreviewoftheliterature