Changes in gene expression associated with FTO overexpression in mice

Changes in gene expression associated with FTO overexpression in mice

Single nucleotide polymorphisms in the first intron of the fat-mass-and-obesity-related gene FTO are associated with increased body weight and adiposity. Increased expression of FTO is likely underlying this obesity phenotype, as mice with two additional copies of Fto (FTO-4 mice) exhibit increased...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Merkestein, M, McTaggart, J, Lee, S, Kramer, H, McMurray, F, Lafond, M, Boutens, L, Cox, R, Ashcroft, F
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	Public Library of Science 2014

Antzeko izenburuak

Changes in gene expression associated with FTO overexpression in mice.
nork: Myrte Merkestein, et al.
Argitaratua: (2014-01-01)

FTO is expressed in neurones throughout the brain and its expression is unaltered by fasting.
nork: McTaggart, J, et al.
Argitaratua: (2011)

FTO is expressed in neurones throughout the brain and its expression is unaltered by fasting.
nork: James S McTaggart, et al.
Argitaratua: (2011-01-01)

Overexpression of Fto leads to increased food intake and results in obesity.
nork: Church, C, et al.
Argitaratua: (2010)

Investigating the role of the fat mass and obesity associated gene (Fto) in obesity
nork: McMurray, F
Argitaratua: (2013)

A dominant mutation in the obesity susceptibility gene FTO results in reduced fat mass with enhanced lipid and carbohydrate metabolism
nork: Church, C, et al.
Argitaratua: (2009)

A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene.
nork: Church, C, et al.
Argitaratua: (2009)

Role of FTO in Adipocyte Development and Function: Recent Insights
nork: Myrte Merkestein, et al.
Argitaratua: (2015-01-01)

Regulation of Fto/Ftm gene expression in mice and humans.
nork: Stratigopoulos, G, et al.
Argitaratua: (2008)

Adult onset global loss of the FTO gene alters body composition and metabolism in the mouse
nork: McMurray, F, et al.
Argitaratua: (2013)

A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene.
nork: Chris Church, et al.
Argitaratua: (2009-08-01)

Adult onset global loss of the fto gene alters body composition and metabolism in the mouse.
nork: Fiona McMurray, et al.
Argitaratua: (2013-01-01)

FTO demethylase activity is essential for normal bone growth and bone mineralization in mice
nork: Sachse, G, et al.
Argitaratua: (2017)

The role of the KATP channel in glucose homeostasis in health and disease: more than meets the islet.
nork: McTaggart, J, et al.
Argitaratua: (2010)

Role for the obesity-related FTO gene in the cellular sensing of amino acids.
nork: Gulati, P, et al.
Argitaratua: (2013)

Effects of activating KATP channel mutations on neuronal function
nork: McTaggart, J, et al.
Argitaratua: (2011)

Loss of FTO antagonises Wnt signaling and leads to developmental defects associated with ciliopathies.
nork: Daniel P S Osborn, et al.
Argitaratua: (2014-01-01)

The Role of FTO Genotype in the Association Between FTO Gene Expression and Anthropometric Measures in Obese and Overweight Adolescent Boys
nork: Saeid Doaei, et al.
Argitaratua: (2019-02-01)

The Spanish ambassadors in the Elizabethan court: collaboration, conflict, and contempt before the Anglo-Spanish War
nork: McTaggart, H
Argitaratua: (2022)

Changes in FTO and IRX3 gene expression in obese and overweight male adolescents undergoing an intensive lifestyle intervention and the role of FTO genotype in this interaction
nork: Saeid Doaei, et al.
Argitaratua: (2019-05-01)

Interactions between macro-nutrients’ intake, FTO and IRX3 gene expression, and FTO genotype in obese and overweight male adolescents
nork: Saeid Doaei, et al.
Argitaratua: (2019-01-01)

A irrealidade do tempo
nork: John McTaggart, et al.
Argitaratua: (2014-12-01)

Early hypothalamic FTO overexpression in response to maternal obesity--potential contribution to postweaning hyperphagia.
nork: Vanni Caruso, et al.
Argitaratua: (2011-01-01)

The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase.
nork: Gerken, T, et al.
Argitaratua: (2007)

Gain-of-function mutations in the K(ATP) channel (KCNJ11) impair coordinated hand-eye tracking
nork: McTaggart, J, et al.
Argitaratua: (2013)

The intention experiment /
nork: 444699 McTaggart, Lynne
Argitaratua: (2007)

The field : the quest for the secret force of the universe /
nork: 444699 McTaggart, Lynne
Argitaratua: (2008)

Verification and validation of ShipMo3D ship motion predictions in the time and frequency domains
nork: Kevin A. McTaggart
Argitaratua: (2011-03-01)

FTO gene expression in diet-induced obesity is downregulated by Solanum fruit supplementation
nork: Asuquo Edeke Affiong, et al.
Argitaratua: (2022-06-01)

Endovascular Treatment of Anterior Circulation Large Vessel Occlusion in the Elderly
nork: Mahesh V. Jayaraman, et al.
Argitaratua: (2018-01-01)

Genetic association of SNPs in the FTO gene and predisposition to obesity in Malaysian Malays
nork: Apalasamy, Y.D., et al.
Argitaratua: (2012)

Genetic association of SNPs in the FTO gene and predisposition to obesity in Malaysian Malays
nork: Y.D. Apalasamy, et al.
Argitaratua: (2012-12-01)

Genetic association of SNPs in the FTO gene and predisposition to obesity in Malaysian Malays
nork: Y.D. Apalasamy, et al.
Argitaratua: (2012-12-01)

Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats.
nork: Yi-Chun Loraine Tung, et al.
Argitaratua: (2010-01-01)

FTO gene variants and consumption of alcoholic beverages
nork: Anna Karolina Flaga, et al.
Argitaratua: (2021-04-01)

FTO Gene Polymorphisms Contribute to the Predisposition and Radiotherapy Efficiency of Nasopharyngeal Carcinoma
nork: Xiao F, et al.
Argitaratua: (2021-09-01)

FTO associations with obesity and telomere length
nork: Yuling Zhou, et al.
Argitaratua: (2017-09-01)

FTO is a relevant factor for the development of the metabolic syndrome in mice.
nork: Kathrin Ikels, et al.
Argitaratua: (2014-01-01)

Association of serum 25-OH-vitamin D level with FTO and IRX3 genes expression in obese and overweight boys with different FTO rs9930506 genotypes
nork: Maryam Gholamalizadeh, et al.
Argitaratua: (2021-08-01)

High risk surveillance outcomes in women with breast cancer gene mutations.
nork: R. McMurray, et al.
Argitaratua: (2024-04-01)