Changes in gene expression associated with FTO overexpression in mice

Changes in gene expression associated with FTO overexpression in mice

Single nucleotide polymorphisms in the first intron of the fat-mass-and-obesity-related gene FTO are associated with increased body weight and adiposity. Increased expression of FTO is likely underlying this obesity phenotype, as mice with two additional copies of Fto (FTO-4 mice) exhibit increased...

书目详细资料
Main Authors:	Merkestein, M, McTaggart, J, Lee, S, Kramer, H, McMurray, F, Lafond, M, Boutens, L, Cox, R, Ashcroft, F
格式:	Journal article
语言:	English
出版:	Public Library of Science 2014

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