Development of chemical probes for the bromodomains of BRD7 and BRD9

The bromodomain family of proteins are 'readers' of acetylated lysines of histones, a key mark in the epigenetic code of gene regulation. Without high quality chemical probes with which to study these proteins, their biological function, and potential use in therapeutics, remains unknown....

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Clark, P, Dixon, D, Brennan, P
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: Elsevier 2016