Development of chemical probes for the bromodomains of BRD7 and BRD9
The bromodomain family of proteins are 'readers' of acetylated lysines of histones, a key mark in the epigenetic code of gene regulation. Without high quality chemical probes with which to study these proteins, their biological function, and potential use in therapeutics, remains unknown....
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Médium: | Journal article |
Jazyk: | English |
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Elsevier
2016
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