The structural basis of ZMPSTE24-dependent laminopathies.

The structural basis of ZMPSTE24-dependent laminopathies.

Бусад хувилбаруудыг харуулах (1)

Mutations in the nuclear membrane zinc metalloprotease ZMPSTE24 lead to diseases of lamin processing (laminopathies), such as the premature aging disease progeria and metabolic disorders. ZMPSTE24 processes prelamin A, a component of the nuclear lamina intermediate filaments, by cleaving it at two s...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Quigley, A, Dong, Y, Pike, A, Dong, L, Shrestha, L, Berridge, G, Stansfeld, P, Sansom, MS, Edwards, A, Bountra, C, von Delft, F, Bullock, A, Burgess-Brown, N, Carpenter, E
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	2013

Ижил төстэй зүйлс

The structural basis of ZMPSTE24-dependent laminopathies
-н: Quigley, A, зэрэг
Хэвлэсэн: (2013)

Mass spectrometry captures off-target drug binding and provides mechanistic insights into the human metalloprotease ZMPSTE24
-н: Mehmood, S, зэрэг
Хэвлэсэн: (2016)

Prelamin A and ZMPSTE24 in premature and physiological aging
-н: Howard J. Worman, зэрэг
Хэвлэсэн: (2023-12-01)

ZMPSTE24 Is Associated with Elevated Inflammation and Progerin mRNA
-н: Moritz Messner, зэрэг
Хэвлэсэн: (2020-08-01)

Requirements for efficient proteolytic cleavage of prelamin A by ZMPSTE24.
-н: Jemima Barrowman, зэрэг
Хэвлэсэн: (2012-01-01)

Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states.
-н: Shintre, C, зэрэг
Хэвлэсэн: (2013)

ZMPSTE24 missense mutations that cause progeroid diseases decrease prelamin A cleavage activity and/or protein stability
-н: Spear, ED, зэрэг
Хэвлэсэн: (2018)

ZMPSTE24 missense mutations that cause progeroid diseases decrease prelamin A cleavage activity and/or protein stability
-н: Eric D. Spear, зэрэг
Хэвлэсэн: (2018-07-01)

Deciphering Nuclear Mechanobiology in Laminopathy
-н: Jungwon Hah, зэрэг
Хэвлэсэн: (2019-03-01)

运用二代测序技术产前诊断ZMPSTE24基因突变
-н: 麦明琴, зэрэг
Хэвлэсэн: (2017-01-01)

The Senolytic Drug Fisetin Attenuates Bone Degeneration in the Zmpste24−/− Progeria Mouse Model
-н: William S. Hambright, зэрэг
Хэвлэсэн: (2023-01-01)

Targeting CK2 eliminates senescent cells and prolongs lifespan in Zmpste24-deficient mice
-н: Jie Zhang, зэрэг
Хэвлэсэн: (2024-05-01)

Inhibition of Arenavirus Entry and Replication by the Cell-Intrinsic Restriction Factor ZMPSTE24 Is Enhanced by IFITM Antiviral Activity
-н: Robert J. Stott-Marshall, зэрэг
Хэвлэсэн: (2022-02-01)

Defining substrate requirements for cleavage of farnesylated prelamin A by the integral membrane zinc metalloprotease ZMPSTE24.
-н: Kaitlin M Wood, зэрэг
Хэвлэсэн: (2020-01-01)

Clinical and genetic characteristics of hereditary laminopathies
-н: E. L. Dadaly, зэрэг
Хэвлэсэн: (2017-02-01)

Clinical and diagnostic difficulties in management of patients with laminopathies
-н: O. V. Melnik, зэрэг
Хэвлэсэн: (2019-11-01)

Accelerated aging in articular cartilage by ZMPSTE24 deficiency leads to osteoarthritis with impaired metabolic signaling and epigenetic regulation
-н: Jinlong Suo, зэрэг
Хэвлэсэн: (2023-05-01)

A Heterozygous ZMPSTE24 Mutation Associated with Severe Metabolic Syndrome, Ectopic Fat Accumulation, and Dilated Cardiomyopathy
-н: Damien Galant, зэрэг
Хэвлэсэн: (2016-04-01)

Deficiency in ZMPSTE24 and resulting farnesyl–prelamin A accumulation only modestly affect mouse adipose tissue stores[S]
-н: Patrick J. Heizer, зэрэг
Хэвлэсэн: (2020-03-01)

Cellular and Animal Models of Striated Muscle Laminopathies
-н: Hannah A. Nicolas, зэрэг
Хэвлэсэн: (2019-03-01)

AN ORPHAN PHENOTYPE OF CARDIOGENITAL LAMINOPATHY — MALOUF SYNDROME
-н: T. G. Vaykhanskaya, зэрэг
Хэвлэсэн: (2016-11-01)

Restrictive Dermopathy Due to ZMPSTE24 Mutation: A Case Report with a Novel Finding of Corpus Callosum Agenesis
-н: Minu Jose Chiramel, зэрэг
Хэвлэсэн: (2024-01-01)

Lamin A/C Mechanotransduction in Laminopathies
-н: Francesca Donnaloja, зэрэг
Хэвлэсэн: (2020-05-01)

Nuclear damages and oxidative stress: new perspectives for laminopathies
-н: G. Lattanzi, зэрэг
Хэвлэсэн: (2012-10-01)

Structural basis for ASPP2 recognition by the tumor suppressor p73
-н: Canning, P, зэрэг
Хэвлэсэн: (2012)

Structural basis for ASPP2 recognition by the tumor suppressor p73.
-н: Canning, P, зэрэг
Хэвлэсэн: (2012)

Cardiac involvement in laminopathies – short invited review
-н: Gerardo Nigro, зэрэг
Хэвлэсэн: (2015-12-01)

Implications and Assessment of the Elastic Behavior of Lamins in Laminopathies
-н: Subarna Dutta, зэрэг
Хэвлэсэн: (2016-10-01)

Inflammatory myopathy in the context of an unusual overlapping laminopathy
-н: Cristina Guillín-Amarelle, зэрэг
Хэвлэсэн: (2018-05-01)

The empowerment of translational research: lessons from laminopathies
-н: Benedetti Sara, зэрэг
Хэвлэсэн: (2012-06-01)

HIV protease inhibitors inhibit FACE1/ZMPSTE24: a mechanism for acquired lipodystrophy in patients on highly active antiretroviral therapy?
-н: Goulbourne, C, зэрэг
Хэвлэсэн: (2010)

Simulations of the BM2 proton channel transmembrane domain from influenza virus B.
-н: Rouse, S, зэрэг
Хэвлэсэн: (2009)

Embryonic Senescence and Laminopathies in a Progeroid Zebrafish Model
-н: Koshimizu, Eriko, зэрэг
Хэвлэсэн: (2011)

Embryonic senescence and laminopathies in a progeroid zebrafish model.
-н: Eriko Koshimizu, зэрэг
Хэвлэсэн: (2011-03-01)

Risk stratification in laminopathies and Emery Dreifuss muscular dystrophy
-н: Abdallah Fayssoil
Хэвлэсэн: (2018-04-01)

Emery-Dreifuss muscular dystrophy: the most recognizable laminopathy
-н: Agnieszka Madej-Pilarczyk, зэрэг
Хэвлэсэн: (2016-03-01)

Aberrant chromatin organization at the nexus of laminopathy disease pathways
-н: Garrett T. Santini, зэрэг
Хэвлэсэн: (2022-12-01)

The farnesyl transferase inhibitor (FTI) lonafarnib improves nuclear morphology in ZMPSTE24-deficient fibroblasts from patients with the progeroid disorder MAD-B
-н: Kamsi O. Odinammadu, зэрэг
Хэвлэсэн: (2023-12-01)

The Integral Membrane Protein ZMPSTE24 Protects Cells from SARS-CoV-2 Spike-Mediated Pseudovirus Infection and Syncytia Formation
-н: Khurts Shilagardi, зэрэг
Хэвлэсэн: (2022-10-01)

Nuclear envelope proteins and chromatin arrangement: a pathogenic mechanism for laminopathies
-н: NM Maraldi, зэрэг
Хэвлэсэн: (2009-06-01)