The structural basis of ZMPSTE24-dependent laminopathies.

Mutations in the nuclear membrane zinc metalloprotease ZMPSTE24 lead to diseases of lamin processing (laminopathies), such as the premature aging disease progeria and metabolic disorders. ZMPSTE24 processes prelamin A, a component of the nuclear lamina intermediate filaments, by cleaving it at two s...

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Váldodahkkit:	Quigley, A, Dong, Y, Pike, A, Dong, L, Shrestha, L, Berridge, G, Stansfeld, P, Sansom, MS, Edwards, A, Bountra, C, von Delft, F, Bullock, A, Burgess-Brown, N, Carpenter, E
Materiálatiipa:	Journal article
Giella:	English
Almmustuhtton:	2013

The structural basis of ZMPSTE24-dependent laminopathies Dahkki Quigley, A, Dong, Y, Pike, A, Dong, L, Shrestha, L, Berridge, G, Stansfeld, P, Sansom, M, Edwards, A, Bountra, C, Von Delft, F, Bullock, A, Burgess-Brown, N, Carpenter, E

Almmustuhtton 2013

Journal article

The structural basis of ZMPSTE24-dependent laminopathies.

The structural basis of ZMPSTE24-dependent laminopathies Dahkki Quigley, A, Dong, Y, Pike, A, Dong, L, Shrestha, L, Berridge, G, Stansfeld, P, Sansom, M, Edwards, A, Bountra, C, Von Delft, F, Bullock, A, Burgess-Brown, N, Carpenter, E

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