Modelling the ATP binding site of RyR2 to rationalise ligand-induced gating behaviour

Modelling the ATP binding site of RyR2 to rationalise ligand-induced gating behaviour

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Lindsay, C, Sitsapesan, M, Chan, WM, Venturi, E, Welch, W, Musgaard, M, Sitsapesan, RM
التنسيق:	Conference item
اللغة:	English
منشور في:	Cell Press 2019

مواد مشابهة

Promiscuous attraction of ligands within the ATP binding site of RyR2 promotes diverse gating behaviour
حسب: Lindsay, C, وآخرون
منشور في: (2018)

Statins bind to cardiac ryanodine receptor (RyR2) channels to alter opening frequency
حسب: Wilson, A, وآخرون
منشور في: (2018)

Impaired ligand regulation of native RyR2 channels in the catecholaminergic polymorphic ventricular tachycardia mutation, RyR2-V2475F(+/−)
حسب: Wilson, A, وآخرون
منشور في: (2019)

Atorvastatin activates skeletal RyR1 channels: towards reducing statin side-effects
حسب: Lindsay, C, وآخرون
منشور في: (2018)

Ca2+-calmodulin increases RyR2 open probability yet reduces ryanoid association with RyR2
حسب: Sigalas, C, وآخرون
منشور في: (2009)

Simvastatin activates single skeletal RyR1 channels but exerts more complex regulation of the cardiac RyR2 isoform
حسب: Venturi, E, وآخرون
منشور في: (2017)

FKBP12 is a high affinity, reversible activator of RyR2, and FKBP12.6 antagonises its actions
حسب: Sitsapesan, R, وآخرون
منشور في: (2010)

The V2475F CPVT1 mutation yields distinct RyR2 channel populations that differ in their responses to cytosolic Ca2+ and Mg2+
حسب: Wilson, AD, وآخرون
منشور في: (2021)

Quantitative RyR1 reduction and loss of calcium sensitivity of RyR1Q1970fsX16+A4329D cause cores and loss of muscle strength
حسب: Elbaz, M, وآخرون
منشور في: (2019)

FKBP12.6 activates RyR1: investigating the amino acid residues critical for channel modulation
حسب: Venturi, E, وآخرون
منشور في: (2014)

Identification of ATP-binding regions in the RyR1 Ca²⁺ release channel.
حسب: Olga B Popova, وآخرون
منشور في: (2012-01-01)

RyR1-related myopathy mutations in ATP and calcium binding sites impair channel regulation
حسب: Qi Yuan, وآخرون
منشور في: (2021-11-01)

Structural insights into transmembrane helix S0 facilitated RyR1 channel gating by Ca2+/ATP
حسب: Risheng Wei, وآخرون
منشور في: (2025-02-01)

The malignant hyperthermia G2435R mutation causes constitutive RYR1 openings
حسب: Humberstone, TM, وآخرون
منشور في: (2021)

Coordinated movement of cytoplasmic and transmembrane domains of RyR1 upon gating.
حسب: Montserrat Samsó, وآخرون
منشور في: (2009-04-01)

RyR1 Is Involved in the Control of Myogenesis
حسب: Amandine Tourel, وآخرون
منشور في: (2025-01-01)

Complex Actions of FKBP12 on RyR1 Ion Channel Activity Consistent with Negative Co-Operativity in FKBP12 Binding to the RyR1 Tetramer
حسب: Spencer J. Richardson, وآخرون
منشور في: (2025-01-01)

Identification of RyR2-PBmice and the effects of transposon insertional mutagenesis of the RyR2 gene on cardiac function in mice
حسب: Qianqian Wang, وآخرون
منشور في: (2019-05-01)

RyR2 and Calcium Release in Heart Failure
حسب: Jean-Pierre Benitah, وآخرون
منشور في: (2021-10-01)

On the Adjacency Matrix of RyR2 Cluster Structures.
حسب: Mark A Walker, وآخرون
منشور في: (2015-11-01)

Expression of voltage-gated Ca2+ channels, Insp3Rs, and RyRs in the immature mouse ovary
حسب: Daniel Bahena-Alvarez, وآخرون
منشور في: (2022-07-01)

Molecular, Subcellular, and Arrhythmogenic Mechanisms in Genetic RyR2 Disease
حسب: Ewan Douglas Fowler, وآخرون
منشور في: (2022-07-01)

The Arianna thread: the matching of S-100 family with the RyR’s muscle receptor
حسب: Giorgio Fano Illic, وآخرون
منشور في: (2020-03-01)

Functional implications of RyR-DHPR relationships in skeletal and cardiac muscles
حسب: CLARA FRANZINI-ARMSTRONG
منشور في: (2004-01-01)

Biophysical characteristics of TRIC-A and TRIC-B channels and their regulation of RYR2: calcium signaling and excitation–contraction in cardiac, skeletal and smooth muscle
حسب: Hu, J, وآخرون
منشور في: (2022)

Attempts to Create Transgenic Mice Carrying the Q3924E Mutation in RyR2 Ca<sup>2+</sup> Binding Site
حسب: Xiao-hua Zhang, وآخرون
منشور في: (2024-12-01)

RyR2 QQ2958 Genotype and Risk of Malignant Ventricular Arrhythmias
حسب: Francesca Galati, وآخرون
منشور في: (2016-01-01)

Voltage-dependent modulation of cardiac ryanodine receptors (RyR2) by protamine.
حسب: Paula L Diaz-Sylvester, وآخرون
منشور في: (2009-12-01)

Dysregulation of RyR Calcium Channel Causes the Onset of Mitochondrial Retrograde Signaling
حسب: Anindya Roy Chowdhury, وآخرون
منشور في: (2020-08-01)

Structure and function of trimeric intracellular cation channels (TRIC) and ryanodine receptors (RyR)
حسب: Hu, J
منشور في: (2021)

Direct regulation of the cardiac ryanodine receptor (RyR2) by O-GlcNAcylation
حسب: Chidinma A Okolo, وآخرون
منشور في: (2023-10-01)

iNOS is not responsible for RyR1 S-nitrosylation in mdx mice with truncated dystrophin
حسب: Ken’ichiro Nogami, وآخرون
منشور في: (2020-07-01)

In vivo RyR1 reduction in muscle triggers a core-like myopathy
حسب: Laurent Pelletier, وآخرون
منشور في: (2020-11-01)

A chemical chaperone improves muscle function in mice with a RyR1 mutation
حسب: Chang Seok Lee, وآخرون
منشور في: (2017-03-01)

Detection of ryanodine receptor G4911E and I4754M mutation sites and analysis of binding modes of diamide insecticides with RyR on Galeruca daurica (Coleoptera: Chrysomelidae)
حسب: Hao Ren, وآخرون
منشور في: (2022-12-01)

Contextual Fear Memory Formation and Destabilization Induce Hippocampal RyR2 Calcium Channel Upregulation
حسب: Jamileth More, وآخرون
منشور في: (2018-01-01)

Aging Impairs Hippocampal- Dependent Recognition Memory and LTP and Prevents the Associated RyR Up-regulation
حسب: Cecilia Hidalgo, وآخرون
منشور في: (2017-04-01)

RyR2 modulates a Ca2+-activated K+ current in mouse cardiac myocytes.
حسب: Yong-Hui Mu, وآخرون
منشور في: (2014-01-01)

A structural model of the pore-forming region of the skeletal muscle ryanodine receptor (RyR1).
حسب: Srinivas Ramachandran, وآخرون
منشور في: (2009-04-01)

Critical role of intracellular RyR1 calcium release channels in skeletal muscle function and disease
حسب: Erick Omar Hernández-Ochoa, وآخرون
منشور في: (2016-01-01)