Super-resolution in situ analysis of active ribosomal DNA chromatin organization in the nucleolus
Ribosomal RNA (rRNA) transcription by RNA polymerase I (Pol I) is the frst key step of ribosome biogenesis. While the molecular mechanisms of rRNA transcription regulation have been elucidated in great detail, the functional organization of the multicopy rRNA gene clusters (rDNA) in the nucleolus is...
| Main Authors: | , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
Nature Research
2020
|