Inhibition of virus attachment to CD4+ target cells is a major mechanism of T cell line-adapted HIV-1 neutralization.

Antibody-mediated neutralization of human immunodeficiency virus type-1 (HIV-1) is thought to function by at least two distinct mechanisms: inhibition of virus-receptor binding, and interference with events after binding, such as virus-cell membrane fusion. Here we show, by the use of a novel virus-...

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Detalles Bibliográficos
Main Authors: Ugolini, S, Mondor, I, Parren, P, Burton, DR, Tilley, SA, Klasse, P, Sattentau, Q
Formato: Journal article
Idioma:English
Publicado: 1997