NAADP: a new second messenger for glucose-induced Ca2+ responses in clonal pancreatic beta cells.

NAADP: a new second messenger for glucose-induced Ca2+ responses in clonal pancreatic beta cells.

Important questions remain concerning how elevated blood glucose levels are coupled to insulin secretion from pancreatic beta cells and how this process is impaired in type 2 diabetes. Glucose uptake and metabolism in beta cells cause the intracellular Ca(2+) concentration ([Ca(2+)](i)) to increase...

書誌詳細
主要な著者:	Masgrau, R, Churchill, G, Morgan, A, Ashcroft, S, Galione, A
フォーマット:	Journal article
言語:	English
出版事項:	2003

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