Synthesis of Cyclic α-Aminophosphonates through Copper Catalyzed Enamine Activation.
A copper-catalyzed tandem cyclization triggered addition strategy that relies on electrophilic enamine activation has been used to synthesize various cyclic α-aminophosphonates derivatives in good to excellent yields. Both five and six membered rings can be generated under mild conditions with high...
| المؤلفون الرئيسيون: | , , , |
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| التنسيق: | Journal article |
| اللغة: | English |
| منشور في: |
Georg Thieme Verlag
2013
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| الملخص: | A copper-catalyzed tandem cyclization triggered addition strategy that relies on electrophilic enamine activation has been used to synthesize various cyclic α-aminophosphonates derivatives in good to excellent yields. Both five and six membered rings can be generated under mild conditions with high regioselectivity. A mechanism based on copper catalyzed enamine activation is proposed. |
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