Expansion of circulating NKG2D+ effector memory T-cells and expression of NKG2D-ligand MIC in granulomaous lesions in Wegener's granulomatosis.

Expansion of circulating NKG2D+ effector memory T-cells and expression of NKG2D-ligand MIC in granulomaous lesions in Wegener's granulomatosis.

Expansion of circulating CD28- T-cells reminiscent of effector memory T-cells (T(EM)) has been reported in Wegener's granulomatosis (WG) recently. To investigate the role of T(EM) in WG, we analyzed the expression of the activating NK-receptor NKG2D and its ligand MIC on circulating T(EM) and i...

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Bibliographic Details
Main Authors: Capraru, D, Müller, A, Csernok, E, Gross, W, Holl-Ulrich, K, Northfield, J, Klenerman, P, Herlyn, K, Holle, J, Gottschlich, S, Voswinkel, J, Spies, T, Fagin, U, Jabs, W, Lamprecht, P
Format: Journal article
Language:English
Published: 2008

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