Targeting OXPHOS and the electron transport chain in cancer; molecular and therapeutic implications
Oxidative phosphorylation (OXPHOS) takes place in mitochondria and is the process whereby cells use carbon fuels and oxygen to generate ATP. Formerly OXPHOS was thought to be reduced in tumours and that glycolysis was the critical pathway for generation of ATP but it is now clear that OXPHOS, at lea...
Hoofdauteurs: | Greene, J, Segaran, A, Lord, S |
---|---|
Formaat: | Journal article |
Taal: | English |
Gepubliceerd in: |
Elsevier
2022
|
Gelijkaardige items
-
Bezielle selectively targets mitochondria of cancer cells to inhibit glycolysis and OXPHOS.
door: Vivian Chen, et al.
Gepubliceerd in: (2012-01-01) -
OXPHOS mediators in acute myeloid leukemia patients: Prognostic biomarkers and therapeutic targets for personalized medicine
door: Amal Kamal Abdel-Aziz
Gepubliceerd in: (2024-11-01) -
Impaired OXPHOS complex III in breast cancer.
door: Kjerstin M Owens, et al.
Gepubliceerd in: (2011-01-01) -
The molecular evolutionary dynamics of oxidative phosphorylation (OXPHOS) genes in Hymenoptera
door: Yiyuan Li, et al.
Gepubliceerd in: (2017-12-01) -
The Molecular Mechanisms behind Advanced Breast Cancer Metabolism: Warburg Effect, OXPHOS, and Calcium
door: Erna Mitaishvili, et al.
Gepubliceerd in: (2024-03-01)