Accounting for unobservable preference heterogeneity and evaluating alternative anchoring approaches to estimate country-specific EQ-5D-Y value sets: a case study using Spanish preference data
<p><strong>Objectives:</strong> The EuroQol Group published the EQ-5D-Y valuation protocol. This protocol suggested the use of two valuation techniques to elicit preferences: Composite Time-Trade-Off (C-TTO) and Discrete Choice Experiments (DCE). The protocol left the decision of w...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Journal article |
| Language: | English |
| Published: |
Elsevier
2021
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| _version_ | 1797107358720065536 |
|---|---|
| author | Ramos-Goñi, JM Oppe, M Estévez-Carrillo, A Rivero-Arias, O |
| author2 | IMPACT HTA HRQoL Group |
| author_facet | IMPACT HTA HRQoL Group Ramos-Goñi, JM Oppe, M Estévez-Carrillo, A Rivero-Arias, O |
| author_sort | Ramos-Goñi, JM |
| collection | OXFORD |
| description | <p><strong>Objectives:</strong> The EuroQol Group published the EQ-5D-Y valuation protocol. This protocol suggested the use
of two valuation techniques to elicit preferences: Composite Time-Trade-Off (C-TTO) and Discrete Choice Experiments (DCE). The protocol left the decision of what modelling approach to use open for researchers. Our aims were to explore modelling strategies allowing generation of EQ-5D-Y value sets and to produce an EQ-5D-Y Spanish value set.</p>
<p><strong>Methods:</strong> We used EQ-5D-Y DCE and C-TTO data collected in Spain following the protocol and adopted
a staged approach for our modelling exercise. First, we selected the best performing DCE latent class model. We tested several of models, including 2-10 classes. We selected the preferred model based on best goodness of fit in terms of the Bayesian information criterion (BIC). We considered 2 anchoring approaches to estimate utility values: 1) pits state anchoring and 2) hybrid models (using all available C-TTO responses). All analysis were weighted to be representative of the Spanish population.</p>
<p><strong>Results:</strong> We collected 1,005 DCE and 200 C-TTO interviews. We selected a DCE model including 4
classes. Hybrid models using all available C-TTO observations produced a narrower range of values than the pits state anchoring approach.</p>
<p><strong>Conclusions:</strong> In this manuscript we have presented an EQ-5D-Y value set that can be used for cost-utility
analysis in Spain. The international EQ-5D-Y valuation protocol should be updated to include a different set of health states for the C-TTO experiment if researchers wish to use alternative anchoring approaches to the “pits state”.</p> |
| first_indexed | 2024-03-07T07:13:26Z |
| format | Journal article |
| id | oxford-uuid:26963f8e-1b3f-4e90-9e10-f540970d63f5 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T07:13:26Z |
| publishDate | 2021 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:26963f8e-1b3f-4e90-9e10-f540970d63f52022-07-28T08:56:09ZAccounting for unobservable preference heterogeneity and evaluating alternative anchoring approaches to estimate country-specific EQ-5D-Y value sets: a case study using Spanish preference dataJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:26963f8e-1b3f-4e90-9e10-f540970d63f5EnglishSymplectic ElementsElsevier2021Ramos-Goñi, JMOppe, MEstévez-Carrillo, ARivero-Arias, OIMPACT HTA HRQoL Group<p><strong>Objectives:</strong> The EuroQol Group published the EQ-5D-Y valuation protocol. This protocol suggested the use of two valuation techniques to elicit preferences: Composite Time-Trade-Off (C-TTO) and Discrete Choice Experiments (DCE). The protocol left the decision of what modelling approach to use open for researchers. Our aims were to explore modelling strategies allowing generation of EQ-5D-Y value sets and to produce an EQ-5D-Y Spanish value set.</p> <p><strong>Methods:</strong> We used EQ-5D-Y DCE and C-TTO data collected in Spain following the protocol and adopted a staged approach for our modelling exercise. First, we selected the best performing DCE latent class model. We tested several of models, including 2-10 classes. We selected the preferred model based on best goodness of fit in terms of the Bayesian information criterion (BIC). We considered 2 anchoring approaches to estimate utility values: 1) pits state anchoring and 2) hybrid models (using all available C-TTO responses). All analysis were weighted to be representative of the Spanish population.</p> <p><strong>Results:</strong> We collected 1,005 DCE and 200 C-TTO interviews. We selected a DCE model including 4 classes. Hybrid models using all available C-TTO observations produced a narrower range of values than the pits state anchoring approach.</p> <p><strong>Conclusions:</strong> In this manuscript we have presented an EQ-5D-Y value set that can be used for cost-utility analysis in Spain. The international EQ-5D-Y valuation protocol should be updated to include a different set of health states for the C-TTO experiment if researchers wish to use alternative anchoring approaches to the “pits state”.</p> |
| spellingShingle | Ramos-Goñi, JM Oppe, M Estévez-Carrillo, A Rivero-Arias, O Accounting for unobservable preference heterogeneity and evaluating alternative anchoring approaches to estimate country-specific EQ-5D-Y value sets: a case study using Spanish preference data |
| title | Accounting for unobservable preference heterogeneity and evaluating alternative anchoring approaches to estimate country-specific EQ-5D-Y value sets: a case study using Spanish preference data |
| title_full | Accounting for unobservable preference heterogeneity and evaluating alternative anchoring approaches to estimate country-specific EQ-5D-Y value sets: a case study using Spanish preference data |
| title_fullStr | Accounting for unobservable preference heterogeneity and evaluating alternative anchoring approaches to estimate country-specific EQ-5D-Y value sets: a case study using Spanish preference data |
| title_full_unstemmed | Accounting for unobservable preference heterogeneity and evaluating alternative anchoring approaches to estimate country-specific EQ-5D-Y value sets: a case study using Spanish preference data |
| title_short | Accounting for unobservable preference heterogeneity and evaluating alternative anchoring approaches to estimate country-specific EQ-5D-Y value sets: a case study using Spanish preference data |
| title_sort | accounting for unobservable preference heterogeneity and evaluating alternative anchoring approaches to estimate country specific eq 5d y value sets a case study using spanish preference data |
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