A chondroprotective role for matrix-bound FGF2

A chondroprotective role for matrix-bound FGF2

Manylion Llyfryddiaeth
Prif Awduron:	Chia, S, Sawaji, Y, Burleigh, A, McLean, C, Saklatvala, J, Vincent, T
Fformat:	Journal article
Cyhoeddwyd:	2009

Eitemau Tebyg

Fibroblast growth factor 2 is an intrinsic chondroprotective agent that suppresses ADAMTS-5 and delays cartilage degradation in murine osteoarthritis.
gan: Chia, S, et al.
Cyhoeddwyd: (2009)

FGF-2 is bound to perlecan in the pericellular matrix of articular cartilage, where it acts as a chondrocyte mechanotransducer.
gan: Vincent, T, et al.
Cyhoeddwyd: (2007)

TSG‐6 is weakly chondroprotective in murine OA but does not account for FGF2‐mediated joint protection
gan: Zhu, L, et al.
Cyhoeddwyd: (2020)

The dependence of FGF2 on murine cartilage injury responses
gan: Chong, K, et al.
Cyhoeddwyd: (2011)

Accelerated disease in a surgical model of murine OA in mice lacking FGF-2
gan: Chia, S, et al.
Cyhoeddwyd: (2007)

Structural and regulatory components of the pericellular matrix of young and mature articular cartilage
gan: McLean, C, et al.
Cyhoeddwyd: (2010)

Pericellular matrix of articular cartilage. A novel mechanotransduction mechanism in articular chondrocytes?
gan: Vincent, T, et al.
Cyhoeddwyd: (2006)

Regulation of secretion of connective tissue growth factor (CTGF) by heparin
gan: McLean, C, et al.
Cyhoeddwyd: (2009)

Connective tissue growth factor: matrix localisation, regulation and possible function in articular cartilage
gan: McLean, C, et al.
Cyhoeddwyd: (2010)

Dickkopf-3 is upregulated in osteoarthritis and has a chondroprotective role
gan: Snelling, S, et al.
Cyhoeddwyd: (2015)

Dexamethasone: chondroprotective corticosteroid or catabolic killer?
gan: Black, Robert Xavier, et al.
Cyhoeddwyd: (2020)

Anti-catabolic effect of fibroblast growth factor-2 in human articular cartilage
gan: Sawaji, Y, et al.
Cyhoeddwyd: (2009)

Chondroprotective factors in osteoarthritis: A joint affair
gan: Mimpen, J, et al.
Cyhoeddwyd: (2019)

Basic FGF mediates an immediate response of articular cartilage to mechanical injury.
gan: Vincent, T, et al.
Cyhoeddwyd: (2002)

Basic fibroblast growth factor (FGF) mediator of the immediate injury response in articular cartilage
gan: Vincent, T, et al.
Cyhoeddwyd: (2001)

Activation of mitogen activated Protein Kinases (MAPKs) and gene induction upon explantation in articular cartilage from wild type and FGF-2(-/-) mice
gan: Chong, K, et al.
Cyhoeddwyd: (2009)

BASIC FIBROBLAST GROWTH FACTOR (bFGF) MEDIATES THE IMMEDIATE INJURY RESPONSE IN ARTICULAR CARTILAGE
gan: Vincent, T, et al.
Cyhoeddwyd: (2002)

INTERLEUKIN 1 INDUCES AGGRECAN DEGRADATION BY HUMAN ARTICULAR CHONDROCYTES THROUGH A TAK1/MKK4/JNK2 PATHWAY WITHOUT INVOLVEMENT OF NFKB
gan: Ismail, H, et al.
Cyhoeddwyd: (2013)

Fibroblast growth factor 2 inhibits induction of aggrecanase activity in human articular cartilage.
gan: Sawaji, Y, et al.
Cyhoeddwyd: (2008)

The role of biomechanical factors in OA development
gan: Burleigh, A, et al.
Cyhoeddwyd: (2010)

Chondroprotective Effect of Zerumbone on Monosodium Iodoacetate Induced Osteoarthritis in Rats
gan: Al-Saffar, F. J., et al.
Cyhoeddwyd: (2010)

THE ROLE OF FIBROBLAST GROWTH FACTOR 2 (FGF2) IN THE CELLULAR RESPONSE TO INJURY FOLLOWING MURINE CARTILAGE EXPLANTATION
gan: Chong, K, et al.
Cyhoeddwyd: (2010)

Evaluation of chondroprotective activity of Channa striatus in rabbit osteoarthritis model
gan: Abdul Kadir, Azidah, et al.
Cyhoeddwyd: (2019)

Investigating the role of FGF signaling in left-right determination
gan: Little, RB
Cyhoeddwyd: (2021)

Interleukin 13 (IL-13)-regulated expression of the chondroprotective metalloproteinase ADAM15 is reduced in aging cartilage
gan: Yang, CY, et al.
Cyhoeddwyd: (2020)

ADAMTS4 and ADAMTS5 are upregulated early in the DMM model of murine OA
gan: Burleigh, A, et al.
Cyhoeddwyd: (2009)

MECHANICAL LOAD DRIVES INFLAMMATORY GENE EXPRESSION AND DISEASE IN MURINE OA
gan: Burleigh, A, et al.
Cyhoeddwyd: (2010)

Towards a resolution of the stoichiometry of the fibroblast growth factor (FGF)-FGF receptor-heparin complex.
gan: Harmer, N, et al.
Cyhoeddwyd: (2004)

Multimers of the fibroblast growth factor (FGF)-FGF receptor-saccharide complex are formed on long oligomers of heparin.
gan: Harmer, N, et al.
Cyhoeddwyd: (2006)

Characterization of Tunable FGF-2 Releasing Polyelectrolyte Multilayers
gan: Macdonald, Mara L., et al.
Cyhoeddwyd: (2013)

FGF-2 promotes osteocyte differentiation through increased E11/podoplanin expression
gan: Ikpegbu, E, et al.
Cyhoeddwyd: (2017)

FGF-2 promotes osteocyte differentiation through increased E11/podoplanin expression
gan: Ikpegbu, E, et al.
Cyhoeddwyd: (2017)

Engineered tissue inhibitor of metalloproteinases-3 variants resistant to endocytosis have prolonged chondroprotective activity
gan: Doherty, C, et al.
Cyhoeddwyd: (2016)

CTGF IS RELEASED FROM THE PERICELLULAR MATRIX OF ARTICULAR CARTILAGE UPON MECHANICAL INJURY, AND CONTROLS THE BIOAVAILABILITY OF TGF beta
gan: Tang, X, et al.
Cyhoeddwyd: (2014)

CTGF is released from the pericellular matrix of articular cartilage upon mechanical injury, and promotes the bioavailability of TGF beta
gan: Tang, X, et al.
Cyhoeddwyd: (2014)

Matrix-bound growth factors are released upon cartilage compression by an aggrecan-dependent sodium flux that is lost in osteoarthritis
gan: Keppie, SJ, et al.
Cyhoeddwyd: (2021)

Characterization of the biological properties of FGF-9
gan: Seet, L, et al.
Cyhoeddwyd: (1996)

Fibroblast Growth Factor 2 (FGF2) in cartilage injury and repair
gan: Khan, S
Cyhoeddwyd: (2018)

Dexamethasone inhibits aggrecanolysis in human articular cartilage but promotes it in porcine tissue
gan: Sawaji, Y, et al.
Cyhoeddwyd: (2009)

Connective Tissue Growth Factor (CTGF) contributes to joint homeostasis and osteoarthritis severity by controlling the matrix sequestration and activation of latent TGFβ
gan: Tang, X, et al.
Cyhoeddwyd: (2018)