A rat CD4 mutant containing the gp120-binding site mediates human immunodeficiency virus type 1 infection.

A rat CD4 mutant containing the gp120-binding site mediates human immunodeficiency virus type 1 infection.

CD4 is the primary receptor for the human immunodeficiency virus type 1 (HIV-1). Early mutational studies implicated a number of residues of CD4, centered in the region 41-59, in binding to gp120. However, further mutational analyses, together with studies using inhibitory antibodies or CD4-derived...

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Bibliographic Details
Main Authors:	Simon, J, Somoza, C, Schockmel, G, Collin, M, Davis, S, Williams, A, James, W
Format:	Journal article
Language:	English
Published:	1993

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