Binding of a peptide from a Streptococcus dysgalactiae MSCRAMM to the N-terminal F1 module pair of human fibronectin involves both modules.

Host invasion by a number of pathogenic bacteria such as staphylococci and streptococci involves binding to fibronectin, a ubiquitous extracellular matrix protein. On the bacterial side, host extracellular matrix adherence is mediated by MSCRAMMs (microbial surface components recognizing adhesive ma...

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Autori principali: Schwarz-Linek, U, Plevin, M, Pickford, A, Höök, M, Campbell, I, Potts, JR
Natura: Journal article
Lingua:English
Pubblicazione: 2001