Stress-related consequences of the coronavirus disease 2019 pandemic on symptoms of Crohn's disease
<p><strong>Objectives:</strong> A link between <span data-value="stress">stress</span> and <span data-value="Crohn’s disease">Crohn’s disease</span> activity suggests an ass...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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Wolters Kluwer Health
2021
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| _version_ | 1797110490672922624 |
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| author | Goodday, SM Travis, S Walsh, A Friend, SH |
| author_facet | Goodday, SM Travis, S Walsh, A Friend, SH |
| author_sort | Goodday, SM |
| collection | OXFORD |
| description | <p><strong>Objectives:</strong> A link between <span data-value="stress">stress</span> and <span data-value="Crohn’s disease">Crohn’s disease</span> activity suggests an association, but results have been conflicting. The purpose of this study was to assess whether the <span data-value="stress">stress</span> related to the <span data-value="coronavirus disease 2019">coronavirus disease 2019</span> (COVID-19) pandemic affected disease activity in patients with <span data-value="Crohn’s disease">Crohn’s disease</span>.</p>
<p><strong>Basic methods:</strong> An anonymous survey was distributed to patients through gastroenterology clinics and networks. Patients were asked to report their <span data-value="Crohn’s disease">Crohn’s disease</span> symptoms in the months prior to the COVID-19 pandemic and again during the early stages of the COVID-19 pandemic using the Manitoba inflammatory bowel disease index in addition to questions about <span data-value="stress">stress</span>, perception of reasons for symptom change and personal impact.</p>
<p><strong>Main results:</strong> Out of 243 individuals with a confirmed diagnosis of <span data-value="Crohn’s disease">Crohn’s disease</span>, there was a 24% relative increase in active symptoms between the pre-COVID-19 period to the during-COVID-19 period (<em>P</em> < 0.0001) reflecting an absolute change from 45 to 56%, respectively. The most frequent reported reason for a change in symptoms was ‘Increased <span data-value="stress">stress</span>/and or feeling overwhelmed’ (118/236), and personal impact of the pandemic was, ‘I’m worrying a lot about the future’ (113/236), both reported by approximately half of respondents.</p>
<p><strong>Principal conclusions:</strong> This study serves as a ‘proof of concept’ demonstrating the impact of a significant and uniquely uniform stressor as a natural experiment on <span data-value="Crohn’s disease">Crohn’s disease</span> activity. The severity of symptoms of <span data-value="Crohn’s disease">Crohn’s disease</span> increased during the COVID-19 pandemic. The primary reported reason for symptom change was an increase in <span data-value="stress">stress</span>, not a change in diet, exercise or other lifestyle behaviours, corroborating the hypothesis that <span data-value="stress">stress</span> affects <span data-value="Crohn’s disease">Crohn’s disease</span> activity.</p> |
| first_indexed | 2024-03-07T07:55:35Z |
| format | Journal article |
| id | oxford-uuid:26d3716f-c8ee-4b26-8641-af651dd0e004 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T07:55:35Z |
| publishDate | 2021 |
| publisher | Wolters Kluwer Health |
| record_format | dspace |
| spelling | oxford-uuid:26d3716f-c8ee-4b26-8641-af651dd0e0042023-08-17T13:17:32ZStress-related consequences of the coronavirus disease 2019 pandemic on symptoms of Crohn's diseaseJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:26d3716f-c8ee-4b26-8641-af651dd0e004EnglishSymplectic ElementsWolters Kluwer Health2021Goodday, SMTravis, SWalsh, AFriend, SH<p><strong>Objectives:</strong> A link between <span data-value="stress">stress</span> and <span data-value="Crohn’s disease">Crohn’s disease</span> activity suggests an association, but results have been conflicting. The purpose of this study was to assess whether the <span data-value="stress">stress</span> related to the <span data-value="coronavirus disease 2019">coronavirus disease 2019</span> (COVID-19) pandemic affected disease activity in patients with <span data-value="Crohn’s disease">Crohn’s disease</span>.</p> <p><strong>Basic methods:</strong> An anonymous survey was distributed to patients through gastroenterology clinics and networks. Patients were asked to report their <span data-value="Crohn’s disease">Crohn’s disease</span> symptoms in the months prior to the COVID-19 pandemic and again during the early stages of the COVID-19 pandemic using the Manitoba inflammatory bowel disease index in addition to questions about <span data-value="stress">stress</span>, perception of reasons for symptom change and personal impact.</p> <p><strong>Main results:</strong> Out of 243 individuals with a confirmed diagnosis of <span data-value="Crohn’s disease">Crohn’s disease</span>, there was a 24% relative increase in active symptoms between the pre-COVID-19 period to the during-COVID-19 period (<em>P</em> < 0.0001) reflecting an absolute change from 45 to 56%, respectively. The most frequent reported reason for a change in symptoms was ‘Increased <span data-value="stress">stress</span>/and or feeling overwhelmed’ (118/236), and personal impact of the pandemic was, ‘I’m worrying a lot about the future’ (113/236), both reported by approximately half of respondents.</p> <p><strong>Principal conclusions:</strong> This study serves as a ‘proof of concept’ demonstrating the impact of a significant and uniquely uniform stressor as a natural experiment on <span data-value="Crohn’s disease">Crohn’s disease</span> activity. The severity of symptoms of <span data-value="Crohn’s disease">Crohn’s disease</span> increased during the COVID-19 pandemic. The primary reported reason for symptom change was an increase in <span data-value="stress">stress</span>, not a change in diet, exercise or other lifestyle behaviours, corroborating the hypothesis that <span data-value="stress">stress</span> affects <span data-value="Crohn’s disease">Crohn’s disease</span> activity.</p> |
| spellingShingle | Goodday, SM Travis, S Walsh, A Friend, SH Stress-related consequences of the coronavirus disease 2019 pandemic on symptoms of Crohn's disease |
| title | Stress-related consequences of the coronavirus disease 2019 pandemic on symptoms of Crohn's disease |
| title_full | Stress-related consequences of the coronavirus disease 2019 pandemic on symptoms of Crohn's disease |
| title_fullStr | Stress-related consequences of the coronavirus disease 2019 pandemic on symptoms of Crohn's disease |
| title_full_unstemmed | Stress-related consequences of the coronavirus disease 2019 pandemic on symptoms of Crohn's disease |
| title_short | Stress-related consequences of the coronavirus disease 2019 pandemic on symptoms of Crohn's disease |
| title_sort | stress related consequences of the coronavirus disease 2019 pandemic on symptoms of crohn s disease |
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